TrialFinder  /  Landscape Report ADHD  ·  2026-10-26 Revasser  /  revasserkernel.com
Landscape Report TrialFinder
SOURCE  ClinicalTrials.gov API v2
GENERATED  2026-10-26
VERSION  v1
SAMPLE  100 of 4907 studies

adhd

The adhd clinical trial landscape includes 4907 actively recruiting trials. Semantic expansion identified 4279 additional trials beyond exact-match search, representing a 681.4% discovery lift across related conditions and therapeutic approaches.

Recruiting
4907
active trials
Expansion Lift
+681.4%
4279 additional trials
Top Sponsor
Stanford University
4 trials
Dominant Phase
NA
62 of 102 sampled
Pipeline Overview
Phase Distribution
NA
62
Phase 1
5
Phase 2
12
Phase 3
3
Phase 4
5
Other
15
Therapeutic Modalities
BEHAVIORAL
62
DEVICE
33
DRUG
33
OTHER
32
PROCEDURE
7
DIAGNOSTIC_TEST
6
DIETARY_SUPPLEMENT
1
COMBINATION_PRODUCT
1
Recruiting vs. Completed (2yr)
Recruiting
4907
Completed
3612
Competitive Landscape
Sponsor Classification
83%
10%
7%
OTHER (24)
FED (3)
NIH (2)
Top Sponsors
SponsorTrialsClass
Stanford University4OTHER
Medical University of South Carolina4OTHER
Centre for Addiction and Mental Health3OTHER
Massachusetts General Hospital2OTHER
University of California, Los Angeles2OTHER
VA Office of Research and Development2FED
National Institute on Drug Abuse (NIDA)2NIH
University of Alabama at Birmingham2OTHER
Weill Medical College of Cornell University2OTHER
VA Boston Healthcare System1FED
Florida State University1OTHER
University Hospital, Montpellier1OTHER
St. Joseph's Healthcare Hamilton1OTHER
University of Regina1OTHER
Al-Quds University1OTHER
Geographic Distribution
Top U.S. States by Trial Density
StateTrialsTop City
California21Los Angeles
Florida15Miami
Texas7Houston
New York7The Bronx
Maryland6Baltimore
South Carolina6Charleston
Massachusetts5Boston
Georgia5Atlanta
Ohio4Cincinnati
Illinois4Chicago
Michigan3Lansing
Alabama2Birmingham
Arkansas2Little Rock
Virginia2Richmond
North Carolina1Denver
Missouri1Columbia
Pennsylvania1Pittsburgh
Idaho1Boise
Nebraska1Omaha
Minnesota1Rochester
Expansion Intelligence
+681.4%
Discovery lift — trials found by semantic expansion that exact-match search misses entirely. This is the gap competitors don't see.
3
Exact
1
Parent
3
Related
5
Comorbid
5
Therapeutic
Top Expansion Terms
  • neurodevelopmental disorder Parent
  • executive function disorder Related
  • sluggish cognitive tempo Related
  • inattentive ADHD Related
  • anxiety Comorbid
  • depression Comorbid
  • substance use disorder Comorbid
  • sleep disorder Comorbid
  • autism spectrum disorder Comorbid
  • stimulant ADHD Therapeutic

These terms are curated from clinical literature — not generated by a language model. Each captures trials that use variant nomenclature for the same underlying condition or therapeutic area.

Key Findings
What This Landscape Means for adhd
high
Standard searches miss 681% of relevant trials for adhd — semantic expansion across related conditions and therapeutic approaches is essential for complete landscape visibility.
4279 additional trials found via expansion vs 628 exact matches
high
Phase 2 volume (12) significantly exceeds Phase 3 (3), indicating a pipeline bottleneck — most candidates are 2-4 years from potential approval.
Phase 2/Phase 3 ratio: 4.0x
Next Steps
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Top Recruiting Trials
20 actively recruiting studies
Mechanisms Underlying the Efficacy of Prolonged Exposure
VA Boston Healthcare System n=50 VA Boston Healthcare System Boston, Massachusetts
Intervention BEHAVIORAL: Prolonged Exposure Therapy for Posttraumatic Stress Disorder — Participation will occur throughout 17 weeks over 15 separate visits during which 10, 60-minute sessions of PE will take...
Eligibility Ages 18 Years – 90 Years
Contact Suzanne Pineles, PhD · 857-364-5906 · suzanne.pineles@va.gov
A Natural History Study of Angelman Syndrome
Massachusetts General Hospital n=40 MGH Lurie Center for Autism Lexington, Massachusetts
Eligibility Ages 1 Year
Contact Riley Shubb · 781-860-1711 · MGHGLOW-AS@mgb.org
Causal Role of Delta-beta Coupling for Goal-directed Behavior in Anhedonic Depression
Florida State University n=72 Florida State University Tallahassee, Florida
Intervention DEVICE: Delta-beta tACS via the Neurocare Direct Current Stimulator Multi-Channel 4 — Stimulation will be delivered via the Neurocare Direct Current Stimulator Multi-Channel 4, an investigational electrical...
Eligibility Ages 18 Years – 65 Years
Contact Justin M Riddle, PhD · 850-645-2389 · jriddle@fsu.edu
NCT05515354 PHASE4
Smoking Cessation and Menstrual Cycle Phase
Centre for Addiction and Mental Health n=1200 Centre for Addiction and Mental Health, Nicotine Dependence Clinic Toronto, Ontario
Intervention OTHER: Timing of nicotine replacement therapy start date — Nicotine replacement therapy and abstinence from smoking are initiated at a specific period with regard to the menstrual...
Eligibility Ages 18 Years – 40 Years, FEMALE only
Contact Laurie A Zawertailo, PhD · 4165358501 · laurie.zawertailo@camh.ca
NCT05681572 PHASE3
Effect of Sedative and Anxiolytic Premedication on Children Experience After General Anesthesia
University Hospital, Montpellier n=1000 Uhmontpellier Montpellier, Montpellier
Intervention DRUG: Midazolam — 45 minutes before entering the operating room, patient receives the oral treatment according to their randomization arm,...
Eligibility Ages 7 Years – 18 Years
Contact Sophie BRINGUIER, PHD · 0467338661 · s-bringuierbranchereau@chu-montpellier.fr
Psychological and Physiological Impact of a Mindfulness-based Intervention on Anxiety Disorders During the Postpartum Period
St. Joseph's Healthcare Hamilton n=50 Women's Health Concerns Clinic, St. Joseph's Healthcare Hamilton Hamilton, Ontario
Intervention BEHAVIORAL: 4-week mindfulness-based intervention — This is the first mindfulness-based intervention specifically designed for postpartum mothers and birthing parents with ...
Eligibility Ages 18 Years, FEMALE only
Contact Sheryl M Green, Ph.D., C.Psych · 905-522-1155 · sgreen@stjosham.on.ca
The PSP Sleep Course: An Online Sleep Intervention for Public Safety Personnel With Self-reported Sleep Difficulties.
University of Regina n=60 University of Regina Regina, Saskatchewan
Intervention BEHAVIORAL: Sleep Course — The Sleep Course was previously developed and evaluated in Australia and has since been tailored to Canadian public safe...
Eligibility Ages 18 Years
Contact Heather D Hadjistavropoulos, PhD · 306-585-5133 · heather.hadjistavropoulos@uregina.ca
Assessing the Impact of Additional Serratus Anterior Block Within 24-Hour on Postoperative Pain After Rhomboid Intercostal Block in VATS Patients
Al-Quds University n=50 Al Ahli hospital Hebron
Intervention PROCEDURE: Rhomboid Intercostal Block (RIB) — Rhomboid Intercostal Block (RIB) A regional anesthesia technique administered under ultrasound guidance for postoperativ...
Eligibility Ages 18 Years – 70 Years
Contact Mohammed Adel Adwan, MD · 00970594393480 · maadwan123m@gmail.com
Social Information Processing in Children: an ocUlo-pupillometric Tool for Standard Evaluation
University Hospital, Tours n=460 Service de Pédopsychiatrie-CHU-TOURS Tours
Intervention OTHER: eye-tracker — Eye-tracker recordings of eye movements, gaze direction and pupillary reactivity
Eligibility Ages 1 Day – 50 Years
Contact Nadia Aguillon-Hernandez, MCU · 0247478840 · nadia.aguillon@univ-tours.fr
NCT07027839 PHASE1
Acute Effects of Alcohol on PET Imaging of Phosphodiesterase-4B (PDE4B)
National Institute of Mental Health (NIMH) n=30 National Institutes of Health Clinical Center Bethesda, Maryland
Intervention DRUG: Intravenous Ethanol — Intravenous ethanol infusion before PET Scan
Eligibility Ages 21 Years – 70 Years
Contact Tara N Turon, C.R.N.P. · (301) 827-6599 · tara.turon@nih.gov
Personalized AI-Driven Models in Cognitive Behavioral Therapy for Anxiety
University of Southern California n=140 University of Southern California Los Angeles, California
Intervention BEHAVIORAL: Explicit CBT SAR Personalization for 6 weeks — College student participants with clinically elevated anxiety will engage in 6 weeks of in-home CBT daily exercises with...
Eligibility Ages 18 Years
NCT06511011 PHASE2
Chinese Medicine in Treating Insomnia
Chinese University of Hong Kong n=76 Hong Kong Institute of Integrative Medicine Shatin
Intervention DRUG: Modified Suan ZaoRen Tang-TianWang BuXin Dan — Chinese medicine granules for 6 weeks
Eligibility Ages 18 Years – 65 Years
Contact Zhixiu Lin · 39436347 · linzx@cuhk.edu.hk
In-patient SCC TMS
University of California, Los Angeles n=30 UCLA TMS Service and Research Service Los Angeles, California
Intervention DEVICE: Open-label TMS — Customized, Open-Label Transcranial Magnetic Stimulation
Eligibility Ages 18 Years – 65 Years
Contact Nikita Vincecruz, BS · 310-825-4781 · nvincecruz@mednet.ucla.edu
Continuous Theta Burst Stimulation for Generalized Anxiety Disorder
Military Hospital 175 n=40 Military Hospital 175 Ho Chi Minh City
Intervention DEVICE: Continuous Theta Burst Stimulation of the Right Posterior Parietal Cortex — Continuous theta burst stimulation (cTBS) is delivered to the right posterior parietal cortex (R-PPC), identified at the...
Eligibility Ages 18 Years – 65 Years
Contact Dang Minh Ly, MD · +84359999741 · drminhdang@outlook.com
rTMS for Depression in Young Adults With Autism
Centre for Addiction and Mental Health n=80 Centre for Addiction and Mental Health Toronto, Ontario
Intervention DEVICE: Active Bilateral Theta Burst Stimulation — A total of 30 active BL-TBS sessions. Stimulation will begin with right DLPFC (cTBS) followed by left DLPFC (iTBS)
Eligibility Ages 16 Years – 35 Years
Contact Viviane Grassmann, PhD · 416-535-8501 · AutismTMS@camh.ca
Changes in Etomidate Dosage in Patients With Insomnia Undergoing Intravenous Anesthesia
Beijing Tiantan Hospital n=840 Beijing Tiantan Hospital Beijing, Beijing Municipality
Intervention OTHER: No interventions, it is a observational study — No interventions, this study is to compare the dosage requirement of etomidate under intravenous anesthesia between inso...
Eligibility Ages 18 Years – 64 Years
Brief Behavioral Treatment for Insomnia in Veterans With Posttraumatic Stress Disorder
VA Office of Research and Development n=200 San Francisco VA Medical Center, San Francisco, CA San Francisco, California
Intervention BEHAVIORAL: Brief Behavioral Treatment for Insomnia (BBTI) — Participants in this arm will receive 4 sessions (30-60 minutes) of a brief behavioral treatment for insomnia called BBT...
Eligibility Ages 18 Years – 75 Years
Contact Shira Maguen, PhD · (415) 221-4810 · shira.maguen@va.gov
NCT07493265 PHASE2
A Study to Evaluate the Efficacy and Safety of E2086 in Adults With Narcolepsy
Eisai Inc. n=64 SDS Clinical Trials, Inc-California-Santa Ana Santa Ana, California
Intervention DRUG: E2086 — E2086 oral tablets.
Eligibility Ages 18 Years
Contact Eisai Medical Information · +1-888-274-2378 · esi_medinfo@eisai.com
Olfactory Function and Model-Based Behavior in People Living With HIV and SUD
National Institute on Drug Abuse (NIDA) n=120 National Institute on Drug Abuse Baltimore, Maryland
Eligibility Ages 18 Years – 65 Years
Contact NIDA IRP Screening Team · (800) 535-8254 · researchstudies@nida.nih.gov
Telehealth Behavioral Activation for Teens
Baylor College of Medicine n=250 Baylor College of Medicine Houston, Texas
Intervention OTHER: Behavioral Activation — All participants will undergo behavioral activation treatment for 8-10 weeks
Eligibility Ages 12 Years – 18 Years
Contact Emily Bivins, B.S. · 713-798-1709 · emily.bivins@bcm.edu