Top Recruiting Trials
20 actively recruiting studies
Assess Fibrin in Brains With AD/ADRD
Massachusetts General Hospital
n=30
Massachusetts General Hospital
Boston, Massachusetts
Intervention DIAGNOSTIC_TEST: PET/MR Imaging — PET/MRI Scan with \[64Cu\]FBP8 as directed by protocol
Eligibility Ages 55 Years – 90 Years
A Study to Learn About Salanersen's (BIIB115) Effects on Movement and Its Safety When Given Before Symptoms Appear in Babies With Genetically Diagnosed Spinal Muscular Atrophy (SMA)
Biogen
n=30
Ann and Robert H Lurie Childrens Hospital of Chicago
Chicago, Illinois
Intervention DRUG: Salanersen — Administered intrathecally
Eligibility Ages 0 Days – 42 Days
PET Imaging of Cyclooxygenases in Neurodegenerative Brain Disease
National Institute of Mental Health (NIMH)
n=184
National Institutes of Health Clinical Center
Bethesda, Maryland
Intervention DRUG: 11C-MC1 — Injected IV followed by PET scanning
Eligibility Ages 18 Years – 99 Years
Augmented Reality BCI Longitudinal Study for Persons With Late Stage ALS
Cognixion
n=10
Cognixion
Santa Barbara, California
Intervention DEVICE: Cognixion ONE — A wearable augmented reality brain computer interface with self contained computer and software to enable communication ...
Eligibility Ages 18 Years
MindEx: A Novel, Multifocal, Cognitive Brain-Machine Interface System
Nader Pouratian
n=2
UT Southwestern Medical Center
Dallas, Texas
Intervention DEVICE: Mind Extender (MindEx) — NeuroPort Multi-Port Arrays allow for the local recording of cerebral cortex. The Mind Extender (MindEx) system is prima...
Eligibility Ages 18 Years – 65 Years
Chinese DENOVO PD Registry
Xiangya Hospital of Central South University
n=300
Xiangya Hospital of Central South University
Changsha, Hunan
Eligibility Ages 30 Years – 75 Years
Non-invasive Brain Stimulation and Exercise Intervention for Patients With Motor Neuron Disease
Chulalongkorn University
n=100
King Chulalongkorn Memorial hospital, The Thai Red Cross Society
Bangkok, Pathumwan
Intervention DEVICE: Personalized rTMS — Personalized repetitive transcranial magnetic stimulation (TMS) together with mixed-reality (MR) exercise
Eligibility Ages 18 Years – 80 Years
MediPD: An Online Mediterranean Diet Program for People Living With Parkinson's Disease
Queen's University, Belfast
n=120
Remote assessments from Centre for Public Health, Queens University Belfast
Belfast
Intervention BEHAVIORAL: MediPD Online Mediterranean Diet Program — MediPD is a 12-week online Mediterranean diet behaviour-change programme for people with Parkinson's disease. It provide...
Eligibility Ages 18 Years
SV2A & TSPO PET Imaging Measures to Reveal Mechanisms of HIV Neuropathogenesis During Antiretroviral Therapy
Yale University
n=70
Yale School of Medicne, Neuro ID Research Program
New Haven, Connecticut
Intervention DRUG: SV2A PET — SV2A PET scan with radiotracer \[11C\]UCB-J for imaging synaptic density in the brain
Eligibility Ages 18 Years – 80 Years
The Effects of fNIRS-based Neurofeedback Training on Balance and Gait in Parkinson's Disease
National Yang Ming Chiao Tung University
n=93
National Yang Ming Chiao Tung University
Taipei, None Selected
Intervention OTHER: fNIRS-based neurofeedback with motor imagery — A multichannel wearable fNIRS (NIRSport2, NIRx Medical Technologies LLC, Glen Head, NY, USA) will be used to detect the ...
Eligibility Ages 40 Years – 85 Years
Comprehensive Assessment of Neurodegeneration and Dementia
McGill University
n=1573
University of Calgary
Calgary, Alberta
Eligibility Ages 50 Years – 90 Years
DapagliFLOzin in Renal AL Amyloidosis (FLORAL)
Barbara Ann Karmanos Cancer Institute
n=20
Karmanos Cancer Institute
Detroit, Michigan
Intervention DRUG: Dapagliflozin — 10mg orally once daily
Eligibility Ages 18 Years
L-THEANINE AND MEDITERRANEAN DIET ON RBD, GI FUNCTION, AND INFLAMMATION IN PARKINSON'S DISEASE
Medipol University
n=52
Medipol Mega Hospital
Istanbul
Intervention DIETARY_SUPPLEMENT: Dietary Supplement — L-theanine supplementation combined with Mediterranean diet for 4 weeks.
Eligibility Ages 50 Years – 80 Years
Broccoli Sprout Extract for Cognitive Function
Pusan National University Yangsan Hospital
n=100
Pusan National University Yangsan Hospital
Yangsan
Intervention DIETARY_SUPPLEMENT: Broccoli sprout extract (BSE) — BSE 1,000 mg/day for 12 weeks
Eligibility Ages 50 Years – 85 Years
Development of Digital Services for Parkinson's Disease
University of Exeter
n=80
University of Exeter
Exeter
Intervention DEVICE: gait with cueing wearable device and neuro-ocular performance — Participants will be invited to participate in the following sequential phases. Participants can participate in Phases a...
Eligibility Ages 18 Years
Characterization of Inclusion Body Myopathy Associated With Paget's Disease of Bone and Frontotemporal Dementia (IBMPFD)
University of California, Irvine
n=50
University of California, Irvine
Irvine, California
Eligibility Ages 18 Years
An Online Physical Activity Coaching Intervention for People With PD in Qatar
Qatar University
n=40
Qatar Rehabilitation Institution
Doha
Intervention OTHER: 8-week personalized self-management program tailored to their individual needs using Engage-Qatar PD. participants will be invited to one face-to-face coaching session and 7 online sessions — The first session will lay the groundwork for the program, in which an orientation of the features of the online forum w...
Eligibility Ages 18 Years
Kimel Family Centre for Brain Health and Wellness
Baycrest
n=450
Baycrest
Toronto, Ontario
Intervention BEHAVIORAL: Physical Activity — Participants can chose (with input from a kinesiologist as required) from courses of varying intensity in our gym, warm ...
Eligibility Ages 50 Years
tDCS on Parkinson's Disease Cognition
University of Manitoba
n=36
University of Manitoba
Winnipeg, Manitoba
Intervention DEVICE: High-definition transcranial direct current stimulation — brain stimulation to increase neuronal excitability in the targeted regions
Eligibility Ages 40 Years
A Study to Investigate OCS Tapering in Adult Participants With Generalized Myasthenia Gravis Treated With Ravulizumab
Alexion Pharmaceuticals, Inc.
n=75
Research Site
Chicago, Illinois
Intervention PROCEDURE: Oral Corticosteroid Tapering Schedule — During the tapering period, participant will follow an Oral Corticosteroid tapering schedule as applicable to the partic...
Eligibility Ages 18 Years