Top Recruiting Trials
20 actively recruiting studies
Mechanisms Underlying the Efficacy of Prolonged Exposure
VA Boston Healthcare System
n=50
VA Boston Healthcare System
Boston, Massachusetts
Intervention BEHAVIORAL: Prolonged Exposure Therapy for Posttraumatic Stress Disorder — Participation will occur throughout 17 weeks over 15 separate visits during which 10, 60-minute sessions of PE will take...
Eligibility Ages 18 Years – 90 Years
Left Bundle Branch Pacing vs Right Ventricular Pacing on AHRE Burden in Patients With Preserved LVEF
University Hospital of Patras
n=244
University General Hospital of Patras
Pátrai
Intervention DEVICE: Right Ventricular Pacing — Implantation of a dual-chamber pacemaker with the ventricular lead placed in the RV septum.
At follow-up, the ventricul...
Eligibility Ages 18 Years
Causal Role of Delta-beta Coupling for Goal-directed Behavior in Anhedonic Depression
Florida State University
n=72
Florida State University
Tallahassee, Florida
Intervention DEVICE: Delta-beta tACS via the Neurocare Direct Current Stimulator Multi-Channel 4 — Stimulation will be delivered via the Neurocare Direct Current Stimulator Multi-Channel 4, an investigational electrical...
Eligibility Ages 18 Years – 65 Years
Smoking Cessation and Menstrual Cycle Phase
Centre for Addiction and Mental Health
n=1200
Centre for Addiction and Mental Health, Nicotine Dependence Clinic
Toronto, Ontario
Intervention OTHER: Timing of nicotine replacement therapy start date — Nicotine replacement therapy and abstinence from smoking are initiated at a specific period with regard to the menstrual...
Eligibility Ages 18 Years – 40 Years, FEMALE only
Assess Fibrin in Brains With AD/ADRD
Massachusetts General Hospital
n=30
Massachusetts General Hospital
Boston, Massachusetts
Intervention DIAGNOSTIC_TEST: PET/MR Imaging — PET/MRI Scan with \[64Cu\]FBP8 as directed by protocol
Eligibility Ages 55 Years – 90 Years
Effect of Sedative and Anxiolytic Premedication on Children Experience After General Anesthesia
University Hospital, Montpellier
n=1000
Uhmontpellier
Montpellier, Montpellier
Intervention DRUG: Midazolam — 45 minutes before entering the operating room, patient receives the oral treatment according to their randomization arm,...
Eligibility Ages 7 Years – 18 Years
Analgesia Methods and Early Mobilization in Geriatric ICU Patients After Major Surgery
Prof. Dr. Cemil Tascıoglu Education and Research Hospital Organization
n=90
University of Health Sciences, Prof. Dr. Cemil Taşçıoğlu City Hospital
Istanbul, Istanbul
Intervention DRUG: Systemic Opioid Analgesia (± Multimodal) — Standard-of-care intravenous opioid-based analgesia, with or without additional non-opioid multimodal agents, administer...
Eligibility Ages 65 Years
Psychological and Physiological Impact of a Mindfulness-based Intervention on Anxiety Disorders During the Postpartum Period
St. Joseph's Healthcare Hamilton
n=50
Women's Health Concerns Clinic, St. Joseph's Healthcare Hamilton
Hamilton, Ontario
Intervention BEHAVIORAL: 4-week mindfulness-based intervention — This is the first mindfulness-based intervention specifically designed for postpartum mothers and birthing parents with ...
Eligibility Ages 18 Years, FEMALE only
The PSP Sleep Course: An Online Sleep Intervention for Public Safety Personnel With Self-reported Sleep Difficulties.
University of Regina
n=60
University of Regina
Regina, Saskatchewan
Intervention BEHAVIORAL: Sleep Course — The Sleep Course was previously developed and evaluated in Australia and has since been tailored to Canadian public safe...
Eligibility Ages 18 Years
An Ethical Approach to Detecting Covert Consciousness
Massachusetts General Hospital
n=70
Massachusetts General Hospital
Boston, Massachusetts
Intervention OTHER: Clinician Questionnaire — Surveys will serve to identify preferences, expectations and concerns among clinicians and researchers surrounding data-...
Eligibility Ages 18 Years
PET Imaging of Cyclooxygenases in Neurodegenerative Brain Disease
National Institute of Mental Health (NIMH)
n=184
National Institutes of Health Clinical Center
Bethesda, Maryland
Intervention DRUG: 11C-MC1 — Injected IV followed by PET scanning
Eligibility Ages 18 Years – 99 Years
Social Information Processing in Children: an ocUlo-pupillometric Tool for Standard Evaluation
University Hospital, Tours
n=460
Service de Pédopsychiatrie-CHU-TOURS
Tours
Intervention OTHER: eye-tracker — Eye-tracker recordings of eye movements, gaze direction and pupillary reactivity
Eligibility Ages 1 Day – 50 Years
Examining Intranasal Oxytocin Augmentation of Brief Couples Therapy for Veterans With PTSD
VA Office of Research and Development
n=240
VA San Diego Healthcare System, San Diego, CA
San Diego, California
Intervention DRUG: Oxytocin nasal spray — Veteran participants will self-administer 40 IU of intranasal oxytocin 30 minutes before the start of each bCBCT session...
Eligibility Ages 18 Years
Peer Facilitated Waitlist Controlled Transportation Study
Temple University
n=180
Pathways To Housing PA
Philadelphia, Pennsylvania
Intervention BEHAVIORAL: Bike-Share Travel Training — Half of the participants not assigned to the waitlist will begin the bike-share intervention arm immediately after the b...
Eligibility Ages 18 Years – 65 Years
Impact of Dietary Knowledge Related to Functional Insulin Therapy in Type 1 Diabetes on the Risk of Eating Disorders
University Hospital, Grenoble
n=100
Grenoble
Grenoble
Eligibility Ages 18 Years
Evaluation of the Role of Luteinizing Hormone (LH) and Human Chorionic Gonadotropin (hCG) in Adult Patients Undergoing Assessment for Endocrine Disorders
Martin Blomberg Jensen
n=20000
Department of Endocrinology and Internal Medicine, Herlev Hospital
Herlev
Eligibility Ages 18 Years – 90 Years
Acute Effects of Alcohol on PET Imaging of Phosphodiesterase-4B (PDE4B)
National Institute of Mental Health (NIMH)
n=30
National Institutes of Health Clinical Center
Bethesda, Maryland
Intervention DRUG: Intravenous Ethanol — Intravenous ethanol infusion before PET Scan
Eligibility Ages 21 Years – 70 Years
Personalized AI-Driven Models in Cognitive Behavioral Therapy for Anxiety
University of Southern California
n=140
University of Southern California
Los Angeles, California
Intervention BEHAVIORAL: Explicit CBT SAR Personalization for 6 weeks — College student participants with clinically elevated anxiety will engage in 6 weeks of in-home CBT daily exercises with...
Eligibility Ages 18 Years
Chinese Medicine in Treating Insomnia
Chinese University of Hong Kong
n=76
Hong Kong Institute of Integrative Medicine
Shatin
Intervention DRUG: Modified Suan ZaoRen Tang-TianWang BuXin Dan — Chinese medicine granules for 6 weeks
Eligibility Ages 18 Years – 65 Years
Recovery With Exogenous Ketones and Antipsychotics
Université de Sherbrooke
n=15
Hotel-Dieu CIUSSS de l'Estrie-CHUS
Sherbrooke, Quebec
Intervention OTHER: Medium chain triglyceride oil — Supplementation with 15 g of medium chain triglyceride oil, a food product commercially available over-the-counter in re...
Eligibility Ages 18 Years – 35 Years