Top Recruiting Trials
20 actively recruiting studies
Optimizing Parameters of Low-Intensity Focused Ultrasound for Pallidal Modulation in Huntington's Disease
First Affiliated Hospital of Fujian Medical University
n=24
Department of Rehabilitation Medicine, The First Affiliated Hospital of Fujian Medical University
Fuzhou, Fujian
Intervention DEVICE: Low-Intensity Focused Ultrasound Stimulation（LIFU） — This is not a traditional three-arm parallel trial but a Stage I/II dose-finding study using an adaptive design. Partici...
Eligibility Ages 18 Years – 75 Years
A Study on the Correlation Between Oral Health and Delirium in Surgical Inpatients
Xinhua Hospital, Shanghai Jiao Tong University School of Medicine
n=550
Shanghai Xinhua hospital
Shanghai, Shanghai Municipality
Intervention OTHER: Oral Frailty — The exposure factor is the presence of oral frailty in patients before surgery, and oral frailty is evaluated using a sc...
Eligibility Ages 18 Years – 90 Years
Dynamic Light Scattering Ocular Measurement in the Detection of Dementia
MD Stem Cells
n=50
3T Radiology
Coconut Creek, Florida
Eligibility Ages 18 Years
Long-term Follow-up of Anxiety and Depression in Patients With Malignant Tumors
Henan Cancer Hospital
n=200
Department of Bone and Soft Tissue ,Henan Cancer Hospital
Zhengzhou, Henan
Intervention OTHER: Hospital Anxiety and Depression Scale — The basic information, anxiety and depression, treatment and prognosis of these patients were collected.
ACT Together: Implementing a Web-Based Program With Brief Coaching for Parents of Children With Disabilities in Pediatric Outpatient Clinics
University of South Florida
n=60
University of South Florida
Tampa, Florida
Intervention BEHAVIORAL: ACT Together — ACT Together includes six self-paced, weekly web-based ACT modules and six brief phone coaching sessions delivered after...
Eligibility Ages 18 Years
Identifying Cerebral Hemodynamic Patterns in Mood Disorders and Mild Cognitive Impairment: A Functional Near-Infrared Spectroscopy (fNIRS) Study
Mayo Clinic
n=200
Mayo Clinic
Rochester, Minnesota
Intervention OTHER: Observational assessment using functional near-infrared spectroscopy (fNIRS), a noninvasive, portable brain imaging tool that measures changes in brain blood flow and oxygen levels. — Functional near-infrared spectroscopy (fNIRS) transcutaneously measures changes in oxyhemoglobin in the prefrontal corte...
Eligibility Ages 18 Years
Perinatal Covid-19 Infection, NO Pathway, and Minipuberty
University Hospital, Lille
n=180
Hop Jeanne de Flandre Chu Lille
Lille
Intervention OTHER: Inhaled NO — Newborn or young infants (\< 3 months) receiving inhaled NO as part of their treatment for severe respiratory failure
Eligibility Ages 3 Months
The Effect of Lavender Inhalation on Anxiety, Sleep, and Blood Pressure
Ardahan University
n=50
Ardahan State Hospital
Ardahan, Ardahan
Intervention OTHER: Lavender — Participants receive lavender oil inhalation three times per week for one month (total of 12 sessions) using a standardi...
Electroacupuncture for Generalized Anxiety Disorder: Clinical Efficacy and Neuroimaging Mechanisms
Lishu Gao
n=123
Affiliated Hangzhou First People's Hospital
Hangzhou, Zhejiang
Intervention PROCEDURE: Electroacupuncture (EA) — Electroacupuncture (EA) is performed at acupoints including GV20 (Baihui), EX-HN1 (Sishencong), GV29 (Shenting), EX-HN16...
Eligibility Ages 18 Years – 60 Years
Alcohol and Sexual Communication Among Couples in the Laboratory
University of Colorado, Denver
n=480
University of Colorado Anschutz Medical Campus
Aurora, Colorado
Intervention OTHER: Direct Communication — Participants assigned to receive direct communication about their sexual preferences from their partner.
Eligibility Ages 21 Years – 65 Years
Psilocybin and Methylenedioxymethamphetamine (MDMA) for Post-traumatic Stress Disorder (PTSD)
Johns Hopkins University
n=40
Johns Hopkins Center for Psychedelic and Consciousness Research
Baltimore, Maryland
Intervention DRUG: Psilocybin — Experimental Psilocybin (exact dosages not disclosed)
Eligibility Ages 21 Years
Anti-Inflammatory Challenge in Schizophrenia
Emory University
n=60
Grady Memorial Hospital
Atlanta, Georgia
Intervention DRUG: Infliximab — Infliximab has FDA approval for the treatment of rheumatoid arthritis and inflammatory bowel syndrome. The current propo...
Eligibility Ages 18 Years – 55 Years
Enhancing Generalization of Virtual Reality Exposure for Public Speaking Anxiety
Philipps University Marburg
n=48
Department of Psychology, Philipps-University of Marburg
Marburg, Hesse
Intervention BEHAVIORAL: VR Exposure — 6 VR speech exposure trials (3 min each; topic: "something you are proud of")
Eligibility Ages 18 Years – 70 Years
Longitudinal Endpoint Assessment of Disease Burden in HD
Huntington Study Group
n=600
Huntington Study Group
Rochester, New York
Eligibility Ages 18 Years
Ejaculatory and Orgasmic Dysfunction Registry
Charitable Union for the Research and Education of Peyronie's Disease
n=500
The Male Fertility and Peyronie's Clinic
Orem, Utah
Eligibility Ages 18 Years
The Effect of a Six Week Intensified Pharmacological Treatment for Major Depressive Disorder Compared to Treatment as Usual in Subjects Who Had a First-time Treatment Failure on Their First-line Treatment.
Dr. Inge Winter
n=418
Medical University Innsbruck
Innsbruck
Intervention DRUG: Esketamine Nasal Product — See arm description
Eligibility Ages 18 Years – 65 Years
Suvorexant: A Dual Orexin Receptor Antagonist for Treating Sleep Disturbance in Posttraumatic Stress
VA Office of Research and Development
n=190
VA Long Beach Healthcare System, Long Beach, CA
Long Beach, California
Intervention DRUG: Suvorexant — Suvorexant, a dual orexin receptor antagonist, is the first in a new class of drugs with great promise of addressing ins...
Eligibility Ages 18 Years – 75 Years
Predictability of the Clinical Global Impression Scale (CGI) in Post Immediate in Psychotraumatic Impact
Centre Hospitalier Arras
n=241
Arras General Hospital
Arras
Eligibility Ages 18 Years
Association Between Body Composition and Pain in Spinal Cord Injury
University of Miami
n=40
University of Miami
Coral Gables, Florida
Intervention OTHER: Moderate Fat Meal — A liquid meal consisting of powdered protein and complex carbohydrates blended with coconut oil and peanut butter in rat...
Eligibility Ages 18 Years – 70 Years
Immersive Nature-Based Wellbeing Program in Older Adults With Cognitive Impairment
Consorci Sanitari de Terrassa
n=230
Consorci Sanitari de Terrassa
Terrassa, Barcelona
Intervention DEVICE: Immersive virtual reality program — Participants receive an immersive virtual reality intervention using nature-based environments. The program consists of ...
Eligibility Ages 65 Years