Top Recruiting Trials
20 actively recruiting studies
Long-term Follow-up of Anxiety and Depression in Patients With Malignant Tumors
Henan Cancer Hospital
n=200
Department of Bone and Soft Tissue ,Henan Cancer Hospital
Zhengzhou, Henan
Intervention OTHER: Hospital Anxiety and Depression Scale — The basic information, anxiety and depression, treatment and prognosis of these patients were collected.
Study of the Effect of Vedolizumab on Intestinal Microecological Changes and Its Efficacy in the Treatment of Ulcerative Colitis
Second Affiliated Hospital, Zhejiang University, School of Medicine
n=30
Second Affiliated Hospital Zhejiang University School of Medicine
Zhengzhou, Hangzhou
Intervention DRUG: Vedolizumab — Recommended dose in patients with UC: 300 mg intravenously at weeks 0, 2, and 6 and every 8 weeks thereafter.
Discontin...
Eligibility Ages 18 Years
Vitamin D2 vs Vitamin D2 Plus Calcitriol in Cholestatic Children With Vitamin D Deficiency
Chulalongkorn University
n=54
King Chulalongkorn Memorial Hospital
Bangkok
Intervention DRUG: Vitamin D2 — Vitamin D2 40,000 IU/week weekly
Eligibility Ages 18 Years
Neoadjuvant Immunotherapy Plus Chemotherapy in Borrmann Type 4 and Large Type 3 Gastric Cancer
Sun Yat-sen University
n=53
Sun Yat-sen University Cancer Center
Guangzhou, Guangdong
Intervention DRUG: Tislelizumab — Tislelizumab 200 mg will be administered systemically on day 1 of each cycle in all participants
Eligibility Ages 18 Years – 75 Years
Perinatal Covid-19 Infection, NO Pathway, and Minipuberty
University Hospital, Lille
n=180
Hop Jeanne de Flandre Chu Lille
Lille
Intervention OTHER: Inhaled NO — Newborn or young infants (\< 3 months) receiving inhaled NO as part of their treatment for severe respiratory failure
Eligibility Ages 3 Months
The Effect of Lavender Inhalation on Anxiety, Sleep, and Blood Pressure
Ardahan University
n=50
Ardahan State Hospital
Ardahan, Ardahan
Intervention OTHER: Lavender — Participants receive lavender oil inhalation three times per week for one month (total of 12 sessions) using a standardi...
Laser vs Electrohydraulic Lithotripsy for Difficult CBD Stones
Mahidol University
n=60
Faculty of Medicine Siriraj Hospital, Mahidol University
Bangkok, Bangkok
Intervention DEVICE: Laser Lithotripsy — Laser Lithotripsy
Eligibility Ages 18 Years
Electroacupuncture for Generalized Anxiety Disorder: Clinical Efficacy and Neuroimaging Mechanisms
Lishu Gao
n=123
Affiliated Hangzhou First People's Hospital
Hangzhou, Zhejiang
Intervention PROCEDURE: Electroacupuncture (EA) — Electroacupuncture (EA) is performed at acupoints including GV20 (Baihui), EX-HN1 (Sishencong), GV29 (Shenting), EX-HN16...
Eligibility Ages 18 Years – 60 Years
Wilson's Disease Treated With D-Penicillamine: Characterization of Skin Damage Secondary to Treatment by Measuring Skin Elasticity
Centre Hospitalier Universitaire de Saint Etienne
n=120
Hospices Civils de Lyon
Bron
Intervention OTHER: Preparation of forearm molds with SILFLO® silicone — Preparation of forearm molds with SILFLO® silicone (MONADERM, Monaco), CE-marked and already used routinely in dermocosm...
Eligibility Ages 12 Years
Pharmacokinetics of Elexacaftor/Tezacaftor/Ivacaftor in Cystic Fibrosis
Istituto Giannina Gaslini
n=50
IRCCS Istituto Giannina Gaslini
Genova
Intervention DRUG: Elexacaftor, Tezacaftor, Ivacaftor — Cystic Fibrosis Transmembrane Regulator (CFTR) modulator therapy
Eligibility Ages 6 Years
A Cohort Study on the Safety of Laparoscopic Resection of 5cm or Larger Gastric Gastrointestinal Stromal Tumors
Fujian Medical University
n=194
Department of Gastric Surgery, Fujian Medical University Union Hospital
Fuzhou, Fujian
Eligibility Ages 18 Years – 75 Years
Simulation-Free Celiac Plexus Pain Ablation Using Stereotactic Body Radiotherapy (SBRT) in Participants With Cancer-Related Celiac Pain
Case Comprehensive Cancer Center
n=5
University Hospitals Seidman Cancer Center, Case Comprehensive Cancer Center
Cleveland, Ohio
Intervention OTHER: Simulation-free workflow — Pre-existing diagnostic images (CTs, PET/CTs, or MRIs) will be imported into the online treatment planning system called...
Eligibility Ages 18 Years
Enhancing Generalization of Virtual Reality Exposure for Public Speaking Anxiety
Philipps University Marburg
n=48
Department of Psychology, Philipps-University of Marburg
Marburg, Hesse
Intervention BEHAVIORAL: VR Exposure — 6 VR speech exposure trials (3 min each; topic: "something you are proud of")
Eligibility Ages 18 Years – 70 Years
Malabsorption Blood Test (MBT) to Determine Exocrine Pancreatic Function and Related Quality of Life in Chronic Pancreatitis
Anna Evans Phillips
n=80
Johns Hopkins Medicine
Baltimore, Maryland
Intervention DRUG: Pancreatic Enzyme Replacement Therapy — 12 participants who are PERT responders in the MBT will be randomized to receive 8 weeks of PERT (144,000 lipase units d...
Eligibility Ages 18 Years
The Miami "EMPIRE" Trial - Eradication of Metastatic Pancreatic Cancer With Immuno-Radiation
Benjamin Spieler
n=20
University of Miami
Miami, Florida
Intervention RADIATION: Stereotactic Body Radiation Therapy — The radiation therapy (RT) prescription biologically effective dose (BED10) goal for tumor (α/β=10) aims to achieve at l...
Eligibility Ages 18 Years
Regional Lymph Node Metastasis and Survival Outcomes in Advanced HCC
Zhongda Hospital
n=300
Zhongda Hospital
Nanjing, Jiangsu
Eligibility Ages 18 Years – 80 Years
Immunohistochemical Algorithm for the Diagnosis and Classification of Hepatocellular Carcinomas With TERT, TP53 and CTNNB1 Mutation
IRCCS Azienda Ospedaliero-Universitaria di Bologna
n=100
IRCCS Azienda Ospedaliero-Universitaria di Bologna
Bologna
Intervention DIAGNOSTIC_TEST: Immunohistochemistry and in situ hybridisation analysis — immunohistochemistry and in situ hybridisation analysis for several markers, including p53, beta-Catenin and albumin, bu...
Eligibility Ages 18 Years
Faecal Microbiota Transplantation for Liver Cirrhosis
University of Aarhus
n=220
Department of Hepatology and Gastroenterology, Aarhus University Hospital
Aarhus
Intervention BIOLOGICAL: Faecal microbiota transplantation — All participant will receive three applications of either FMT or placebo and afterwards followed for 1 year.
Eligibility Ages 18 Years – 75 Years
Beneficial Effect of Silymarin in Ulcerative Colitis
Tanta University
n=44
Mabarra Hospital
Asyut
Intervention DIETARY_SUPPLEMENT: Silymarin — Silymarin (milk thistle), an extract obtained from Silybum marianum seeds containing a complex of flavonolignans with a ...
Eligibility Ages 18 Years – 65 Years
AI-Assisted Chemotherapy Side Effect Management
Incheon St.Mary's Hospital
n=174
Incheon St. Mary's Hospital, College of Medicine, The Catholic University of Korea
Incheon
Intervention BEHAVIORAL: LLM-assisted chemotherapy side effect management — Healthcare providers collect patient symptoms during clinic visits, anonymize the information, and input it into the LLM...
Eligibility Ages 18 Years