Top Recruiting Trials
20 actively recruiting studies
A Study to Assess the Safety, Tolerability, and Efficacy of NDI-219216 in Patients With Advanced Solid Tumors.
Nimbus Wadjet, Inc.
n=134
USC Norris Comprehensive Cancer Center
Los Angeles, California
Intervention DRUG: NDI-219216 — NDI-219216 is a highly selective small molecule inhibitor of WRN helicase activity.
Eligibility Ages 18 Years – 99 Years
Anrikefon vs Nalfurafine for Sleep Quality in Hemodialysis Patients With CKD-aP
Zhujiang Hospital
n=50
Zhujiang Hospital, Southern Medical University, No. 253 Gongye Road, Guangzhou, 510282, China
Guangzhou, Guangdong
Intervention DRUG: Anrikefon — intravenous administration
Eligibility Ages 18 Years – 75 Years
Natural History and Longitudinal Clinical Assessments in NCL / Batten Disease, the International DEM-CHILD Database
Universitätsklinikum Hamburg-Eppendorf
n=500
University Medical Center Hamburg-Eppendorf
Hamburg
Intervention OTHER: Natural History — Natural History and Clinical Follow Up.
Fecal Microbiota Transplantation for Obese Women With Polyendocrine Metabolic Ovarian Syndrome
Shanghai Changzheng Hospital
n=161
Center for Reproductive Medicine,Shanghai Changzheng Hospital
Shanghai, Shanghai Municipality
Intervention BIOLOGICAL: oral Fecal Microbiota Transplantation — Participants will receive standardized oral FMT freeze-dried powder capsules without antibiotic pretreatment. The capsul...
Eligibility Ages 20 Years – 40 Years, FEMALE only
Efficacy of a Smartphone App. Designed to Manage Craving & Individual Predictors of Substance Use/Addictive Behavior
Centre Hospitalier Charles Perrens, Bordeaux
n=274
Centre Hospitalier Charles PERRENS
Bordeaux
Intervention OTHER: Smartphone application — Ecological Momentary Assessment (EMA)
: ambulatory assessment of behaviors/symptoms in real-time on smartphones
Eligibility Ages 18 Years
Lifestyle Interventions to Prevent Cognitive Deficits in Subjects With Depressive Symptoms: From Mechanisms to Clinical Practice
IRCCS Centro San Giovanni di Dio Fatebenefratelli
n=120
IRCCS Centro San Giovanni di Dio Fatebenefratelli
Brescia
Intervention BEHAVIORAL: Mediterranean Diet — Participants will receive only the educational intervention about the Mediterranean diet. The program consists of 4-5 on...
Eligibility Ages 50 Years – 80 Years
Pathophysiological Endotyping Using Baseline Polysomnography Data
University Hospital, Antwerp
n=1000
Antwerp University Hospital
Edegem
Intervention PROCEDURE: Drug-induced sleep endoscopy — Endoscopy during drug-induced sleep
Eligibility Ages 18 Years
Comfort Intervention in PICU Children
Ankara Yildirim Beyazıt University
n=86
Ordu Universitesi Egitim ve Arastirma Hastanesi
Ordu, Altınordu
Intervention BEHAVIORAL: Intervention Family-Centered Comfort — Storytelling with the mother's voice, dimmed lighting, and weighted blanket administered by the researcher to children i...
Eligibility Ages 5 Years – 10 Years
Light Flashes to Treat Delayed Sleep Phase Disorder (DSPD)
Stanford University
n=20
Stanford University
Palo Alto, California
Intervention DEVICE: Flashes — one hour of a sequence of light flashes (4000 lux, 3 msec, every 30 seconds); occurs during the hour immediately prior t...
Eligibility Ages 15 Years – 19 Years
Developing a Music Listening mHealth Intervention for Stress Reduction in Early Recovery
Washington State University
n=30
Washington State University Research Clinic
Spokane, Washington
Eligibility Ages 18 Years – 35 Years
Triage Survey for Psychiatry Research Eligibility
Adams Clinical
n=20000
Adams Clinical, Boston
Boston, Massachusetts
Intervention OTHER: Survey — Participants will be surveyed on demographics, medical history, and current psychiatric symptoms. Vital signs, urine dru...
Eligibility Ages 18 Years
Efficacy Investigation of the Medical Device Apneal® on Smartphone for Sleep Apnea-Hypopnea Syndrome Diagnosis
Mitral
n=500
Centre de pneumologie et sommeil
Aix-en-Provence
Intervention DEVICE: Apneal device — Patients will wear a smartphone with the Apneal Application on their chest, while they perform polysomnography
Eligibility Ages 18 Years
Sleep and Rehearsal-Driven Memory in Epilepsy
Hospices Civils de Lyon
n=20
Service de neurologie fonctionnelle et d'épileptologie, Hôpital neurologique Pierre Wertheimer
Bron
Intervention OTHER: Cognitive memory task on a computer — Encoding: (1) Participants will learn 60 associations between pairs of items (cue and target) that are presented sequent...
Eligibility Ages 18 Years – 65 Years
Pilot Project on Interdisciplinary Therapy of Obesity
University of Hohenheim
n=480
University of Heidelberg
Heidelberg
Intervention PROCEDURE: Laparoscopic gastric sleeve — Laparoscopic gastric sleeve
Eligibility Ages 18 Years – 65 Years
Smoking Cessation Program With CBT and Mindfulness Audio Support: A Randomized Controlled Trial
Sir Run Run Shaw Hospital
n=2000
Sir Run Run Shaw Hospital
Hangzhou
Intervention OTHER: cognitive behaviour thearpy — Participants will access the CBT text materials through a dedicated platform
Eligibility Ages 18 Years – 65 Years
Effectiveness of CAT-GSH for Returning Patients
University of Sheffield
n=100
Tameside and Glossop NHS Talking Therapies Service
Ashton-under-Lyne
Intervention BEHAVIORAL: Cognitive analytic therapy guided self-help (CAT-GSH) — Six session CAT-GSH treatment
Eligibility Ages 16 Years
Perinatal Depression & Anxiety (PDA) and Maternal Gut Microbiome
The Canadian College of Naturopathic Medicine
n=100
Sunnybrook Health Science Center
Toronto, Ontario
Intervention DIETARY_SUPPLEMENT: Fish oil — 1500mg EPA +1000mg DHA daily
Eligibility Ages 18 Years – 43 Years, FEMALE only
BioClock: Bright Light Therapy for Depressive Disorders
Universiteit Leiden
n=231
GGzE - Mental Health Institute of Eindhoven and the Kempen
Eindhoven
Intervention PROCEDURE: Bright Light Therapy — In this study, Bright Light Therapy (BLT) will be administered according to Dutch depression guidelines, using Innolux L...
Eligibility Ages 18 Years – 65 Years
Preoperative Sleep Quality and Postoperative Outcomes in Breast Surgery
Dr Abdurrahman Yurtaslan Ankara Oncology Training and Research Hospital
n=150
Dr. Abdurrahman Yurtaslan Ankara Oncology Education and Research Hospital Clinic of Anesthesiology and Rea
Ankara, Yenimahalle
Intervention OTHER: Preoperative Sleep Quality Assessment (PSQI) — Preoperative sleep quality will be assessed using the Pittsburgh Sleep Quality Index (PSQI), a validated self-reported q...
Eligibility Ages 18 Years – 70 Years, FEMALE only
Efficacy of Written Versus Video Patient Education Materials for Postmastectomy Breast Reconstruction
University of California, San Francisco
n=100
University of California, San Francisco
San Francisco, California
Intervention OTHER: Questionnaires — Participants will complete health related questionnaires.
Eligibility Ages 18 Years