Top Recruiting Trials
20 actively recruiting studies
A Phase I Study of ABSK211 in Participants With Advanced Solid Tumors With KRAS Alteration
Abbisko Therapeutics Co, Ltd
n=247
Fudan University Shanghai Cancer Center
Shanghai, Shanghai Municipality
Intervention DRUG: ABSK211 — During the escalation part ,all participants will firstly receive a single dose of ABSK211 as a run-in period to access ...
Eligibility Ages 18 Years
Efficacy and Safety of Concurrent PD-1 Inhibitor and Radiotherapy With Immunonutrition for Esophageal Squamous Cell Carcinoma
Cancer Institute and Hospital, Chinese Academy of Medical Sciences
n=57
Department of Radiation Oncology, Cancer Institute and Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College
Beijing, Beijing Municipality
Intervention RADIATION: Radiotherapy — Interventions consist of 50-60 Gy in 25-30 fractions of radiotherapy.
Eligibility Ages 18 Years – 80 Years
A First-in-Human Study of BG-C0979 in Adults With Advanced Solid Tumors
BeOne Medicines
n=84
Dana Farber Cancer Institute
Boston, Massachusetts
Intervention DRUG: BG-C0979 — Administered by intravenous infusion.
Eligibility Ages 18 Years
A Study to Evaluate Efficacy, and Safety of QL2107 Plus Chemo and Compare With Keytruda in Participants With IV nqNSCLC
Qilu Pharmaceutical Co., Ltd.
n=808
Shandong First Medical University Cancer Hospital
Jinan, Shandong
Intervention DRUG: QL2107 — 200mg on day 1 of each 21-day cycle of the study
Eligibility Ages 18 Years – 75 Years
Prediction of Outcome to Neoadjuvant Therapy in Non-small Cell Lung Cancer（NSCLC）
Qian Chu
n=500
Tongji hospital
Wuhan, Hubei
Eligibility Ages 18 Years
Hypofractionated, 3-week, Preoperative Proton or X-ray Radiotherapy for Patients With Localized Soft Tissue Sarcoma
Oslo University Hospital
n=110
Haukeland University Hospital
Bergen
Intervention RADIATION: preoperative — The radiotherapy will be delivered 2.85 Gy x 15 for both x-ray or proton radiotherapy. A comparative doseplan will decid...
Eligibility Ages 18 Years
SBRT + PD-1 Antibody in Unresectable Locally Recurrent Rectal Cancer（SPARKLE）
Sixth Affiliated Hospital, Sun Yat-sen University
n=31
Sixth Affiliated Hospital, Sun Yat-sen University
Guangzhou, Guangdong
Intervention RADIATION: Stereotactic Body Radiation Therapy (SBRT) — Patients will begin SBRT treatment within 2 weeks after the first round of chemotherapy. Intensity-modulated radiation t...
Eligibility Ages 18 Years – 75 Years
Long-term Follow-up of Anxiety and Depression in Patients With Malignant Tumors
Henan Cancer Hospital
n=200
Department of Bone and Soft Tissue ,Henan Cancer Hospital
Zhengzhou, Henan
Intervention OTHER: Hospital Anxiety and Depression Scale — The basic information, anxiety and depression, treatment and prognosis of these patients were collected.
Preoperative Prediction of Lymph Node Metastasis in T1N0M0 Papillary Thyroid Carcinoma by Using Contrast-enhanced Ultrasound
Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
n=600
Sun Yat-sen Memorial Hospital
Guangdong, Guangzhou
Standard Systemic Therapy Combined With High/Low-dose Radiotherapy Plus Toripalimab for Metastatic Colorectal Cancer
Fudan University
n=96
Fudan University Shanghai Cancer Center
Shanghai, Shanghai Municipality
Intervention DRUG: standard systemic therapy combined with high/low-dose radiotherapy plus toripalimab — First-line standard systemic therapies in cohort A include: FOLFOX/XELOX+ bevacizumab, FOLFOX/XELOX+cetuximab (KRAS/NRAS...
Eligibility Ages 18 Years – 75 Years
FaR-RMS: An Overarching Study for Children and Adults With Frontline and Relapsed RhabdoMyoSarcoma
University of Birmingham
n=1672
Queensland Children's Hospital
Brisbane
Intervention DRUG: Irinotecan — antineoplastic enzyme inhibitor
A Study of Lifileucel (Tumor-infiltrating Lymphocytes) in Adults With Advanced Endometrial Cancer.
Iovance Biotherapeutics, Inc.
n=60
Honor Health
Phoenix, Arizona
Intervention BIOLOGICAL: Lifileucel — A tumor sample is resected from each patient and cultured ex vivo to expand the population of tumor infiltrating lymphoc...
Eligibility Ages 18 Years – 70 Years, FEMALE only
ChemoINTEL Assay Algorithm Development Study: In-Vitro Cytotoxic Drug Induced Apoptosis Correlation with Patient Clinical Response to Administered Chemotherapy in Patients
Pierian Biosciences
n=100
Liverpool Women's NHS Foundation Trust
Liverpool, Merseyside
Intervention OTHER: No intervention — No intervention
Eligibility Ages 18 Years, FEMALE only
Feasibility and Acceptability of Wearable Sensors and ePROs in Early Phase Clinical Trials
Case Comprehensive Cancer Center
n=30
Case Comprehensive Cancer Center, Cleveland Clinic Foundation Taussig Cancer Institute
Cleveland, Ohio
Intervention DEVICE: Wearable actigraphy — Participants will wear an actigraphy for 4 weeks. Participants who already use a smartwatch may opt to utilize their sma...
Eligibility Ages 18 Years
Neoadjuvant Immunotherapy Plus Chemotherapy in Borrmann Type 4 and Large Type 3 Gastric Cancer
Sun Yat-sen University
n=53
Sun Yat-sen University Cancer Center
Guangzhou, Guangdong
Intervention DRUG: Tislelizumab — Tislelizumab 200 mg will be administered systemically on day 1 of each cycle in all participants
Eligibility Ages 18 Years – 75 Years
Dose-escalation Study to Assess Safety and Pharmacokinetics of Nab-Sirolimus in Patients With Locally Advanced or Metastatic Solid Tumors and Moderate Liver Impairment
Aadi Bioscience, Inc.
n=28
South Texas Accelerated Research Therapeutics, LLC
San Antonio, Texas
Intervention DRUG: nab-sirolimus — This is a phase 1, multi-center, open-label, dose-escalation study of nab-sirolimus in adult patients with locally advan...
Eligibility Ages 18 Years
Pioglitazone-Metformin Combination Treatment for High Risk Oral Preneoplasia
University of Minnesota
n=36
University of Minnesota
Minneapolis, Minnesota
Intervention DRUG: pioglitazone-metformin — Treatment with pioglitazone-metformin (15mg/500mg) twice a day for 12 weeks
Eligibility Ages 18 Years
ABlative Radiotherapy (for) Unfavorable Prostate Tumors
University of Milano Bicocca
n=30
Radiation Oncology, ASST Monza (University of Milan Bicocca)
Monza, MB
Eligibility Ages 18 Years – 90 Years, MALE only
Aromatherapy Inhaler Use for HSCT Distress
Stanford University
n=50
Stanford University
Stanford, California
Intervention OTHER: Aromatherapy Stick — Participants receive aromatherapy inhaler education and an aromatherapy stick for self-administered inhalation during th...
Eligibility Ages 18 Years
"Xijiang Project" Screening Cohort for NPC
Ming-Yuan Chen
n=1000000
The Fifth Affiliated Hospital of Sun Yat-sen University
Zhuhai, Guangdong
Intervention DIAGNOSTIC_TEST: EBV antibodies test — Test for VCA-IgA, EBNA1-IgA, EA-IgA, Zta-IgA, Rta-IgG and P85-Ab in nasopharyngeal brushing and plasma in plasma, saliva...
Eligibility Ages 30 Years – 69 Years