Top Recruiting Trials
20 actively recruiting studies
Biofeedback in Idiopathic Infantile Nystagmus Syndrome
Monica Daibert Nido
n=34
CNIB
Toronto, Ontario
Intervention DEVICE: Biofeedback Training — Microperimeter biofeedback training as described provides to the patient a variable frequency sound and a luminous stimu...
Eligibility Ages 5 Years – 17 Years
VR and Orthoses for Rehabilitation in Multiple Sclerosis
Azienda Usl di Bologna
n=12
IRCCS Istituto delle Scienze Neurologiche di Bologna - AUSL of Bologna
Bologna, Bologna
Intervention OTHER: VR and walking brace-based gait rehabilitation — The study implements the use of VR and wearable sensors to enhance gait analysis in clinical practice. Participants will...
Eligibility Ages 18 Years – 65 Years
"Balance, Gait, and Motion Analysis in Multiple Sclerosis"
University of Patras
n=40
Division of Physical Medicine and Rehabilitation/Department of Surgery, University of Ioannina Medical School
Ioannina
Eligibility Ages 18 Years
Neurodegenerative Diseases Progression Markers (MARKERS-NDD)
Casa di Cura San Raffaele Cassino
n=600
San Raffaele Cassino
Cassino, Frosinone
Intervention OTHER: Observation — In MARKERS-NDD up to 600 participants will be enrolled and followed longitudinally once identified, over the course of 1...
Eligibility Ages 10 Years
High-Intensity, Dynamic-stability Gait Training in People With Multiple Sclerosis
Marquette University
n=150
Rehabilitation Hospital of Indiana
Indianapolis, Indiana
Intervention PROCEDURE: High-Intensity Treadmill Training — Participants will walk on a treadmill at a speed that produces 70-80% of age-adjusted heart rate reserve or a rating of ...
Eligibility Ages 18 Years – 75 Years
Investigating Neural Biomarkers for Gait in Parkinson's Patients
Swiss Federal Institute of Technology
n=60
Cereneo
Vitznau, Canton of Lucerne
Intervention DIAGNOSTIC_TEST: Neural Activity Recording — Neural Activity is measured using EEG in all groups. Additionally, in Parkinson's patients, local-field-potentials from ...
Eligibility Ages 18 Years
A Study to Evaluate the Efficacy, PK, Safety, and Tolerability of VIM0423 in Adults With Parkinson's Disease Tremor Insufficiently Responsive to Dopaminergic Therapy
Vima Therapeutics
n=80
Vima Site #039
Scottsdale, Arizona
Intervention DRUG: VIM0423 — VIM0423 is a combination drug product containing two active ingredients (VMA-1001 and VMA-1002)
Eligibility Ages 18 Years – 65 Years
Cerebellar Transcranial Alternating Current Stimulation (tACS) to Modulate Parkinson's Disease Tremor
Universitätsklinikum Hamburg-Eppendorf
n=10
Universitätsklinikum Hamburg-Eppendorf
Hamburg, Free and Hanseatic City of Hamburg
Intervention DEVICE: Active-tACS — 30 seconds of closed-loop tACS at 2-4 mA, with 6 alternating phase alignments and 1-3 repetitions. Phase alignment is ad...
Eligibility Ages 18 Years
Efficacy of Trans-spinal Magnetic Stimulation on Functional Mobility in Chronic Stroke Patients
Universidade Federal de Pernambuco
n=30
Federal University of Paraiba
João Pessoa, Paraíba
Intervention DEVICE: Trans-spinal magnetic stimulation — Trans-spinal magnetic stimulation activates afferent spinal roots and increases cortical excitability.
Eligibility Ages 18 Years – 75 Years
Using Transcranial Magnetic Stimulation (TMS) to Understand Hallucinations in Schizophrenia
Mclean Hospital
n=68
McLean Hospital
Belmont, Massachusetts
Intervention DEVICE: Repetitive Transcranial Magnetic Stimulation (rTMS) — rTMS is a technique of TMS that allows for selective external manipulation of neural activity in a non-invasive manner. ...
Eligibility Ages 18 Years – 55 Years
Understanding Disorder-specific Neural Pathophysiology in Laryngeal Dystonia and Voice Tremor
Massachusetts Eye and Ear Infirmary
n=165
Massachusetts Eye and Ear and University of California San Francisco
Boston, Massachusetts
Intervention OTHER: Brain imaging — Brain images will be conducted with function MRI, magnetoencephalography (MEG), and electroencephalography (EEG) to iden...
Eligibility Ages 18 Years – 80 Years
Neurosurgical Outcome Network
Fondazione I.R.C.C.S. Istituto Neurologico Carlo Besta
n=4500
1. ASST Papa Giovanni XXIII
Bergamo, BG
Eligibility Ages 18 Years
Foot Strengthening to Improve Balance and Gait in Older Adults
Indiana University
n=160
School of Public Health-Bloomington
Bloomington, Indiana
Intervention DEVICE: Minimalist footwear — Habitual use of low-cushion, low-structure footwear designed to increase intrinsic foot muscle engagement during daily a...
Eligibility Ages 45 Years
Cerebellar tDCS in Children With Autism Spectrum Disorder
University of Texas Southwestern Medical Center
n=60
Children's Medical Center
Dallas, Texas
Intervention DEVICE: tDCS — A current of 1 mA will be administered for 20 minutes of with either anodal or cathodal tDCS administration to the right...
Eligibility Ages 4 Years – 17 Years
Posterior Fossa Intracranial Pressure (ICP) Measurement: Clinical Study
University of Valencia
n=12
Hospital General Universitario de Valencia
Valencia, Valencia
Intervention PROCEDURE: Posterior fossa intracranial pressure measurement — Measurement of posterior fossa pressure in an invasive way
Eligibility Ages 18 Years – 80 Years
Application of Thoracic Epidural SCS for Managing FOG in Patients With Advanced Parkinson's Disease
National Taiwan University Hospital
n=5
National Taiwan University Hospital Hsin-Chu Branch
Hsinchu, Hsinchu City
Intervention DEVICE: SCS electrode stimulation 1 — 300Hz/300us
Eligibility Ages 40 Years – 85 Years
Impact of Mirror Therapy Combined With Conventional Training on Gait and Lower Limb Motor Function Among Post-Stroke Patients
Ibadat International University, Islamabad
n=52
Department of Physical Therapy at suleman medical complex hospital, Quetta.
Quetta, Balochistan
Intervention OTHER: Mirror Therapy Based Functional Training — (Basic) - Sitting position:
* Ankle dorsiflexion/plantarflexion (simulating pressing a gas pedal)
* Knee extension/flex...
Eligibility Ages 40 Years – 70 Years
Biomarker Research in Inherited Movement Disorders
Assistance Publique - Hôpitaux de Paris
n=4000
Hôpital Pitié Salpetrière
Paris
Intervention OTHER: Clinical follow-up — Clinical Follow-up:
demographic data and history,
* Retrospective interview (collection of data useful for genetic stu...
Eligibility Ages 7 Years
Locomotor Training With Testosterone to Promote Bone and Muscle Health After Spinal Cord Injury
North Florida Foundation for Research and Education
n=21
North Florida/South Georgia Veterans Health System
Gainesville, Florida
Intervention DRUG: Testosterone Enanthate — Subjects receive testosterone (100 mg/week) by intramuscular injection
Eligibility Ages 18 Years, MALE only
Evaluating the Impact of Virtual Reality on Mood in Patients Undergoing Magnetic Resonance-Guided Focused Ultrasound for Medication-Refractory Essential Tremor
Sunnybrook Health Sciences Centre
n=60
Sunnybrook Health Sciences
North York, Ontario
Intervention DEVICE: VR headset: video number 1 — A 6-minute virtual reality (VR) video that contains sights and sounds that might affect mood. The video is viewed on a M...
Eligibility Ages 18 Years