TrialFinder  /  Landscape Report CEREBELLAR COGNITIVE AFFECTIVE SYNDROME  ·  2026-10-26 Revasser  /  revasserkernel.com
Landscape Report TrialFinder
SOURCE  ClinicalTrials.gov API v2
GENERATED  2026-10-26
VERSION  v1
SAMPLE  100 of 315 studies

cerebellar cognitive affective syndrome

The cerebellar cognitive affective syndrome clinical trial landscape includes 315 actively recruiting trials. Semantic expansion identified 313 additional trials beyond exact-match search, representing a 15650% discovery lift across related conditions and therapeutic approaches.

Recruiting
315
active trials
Expansion Lift
+15650%
313 additional trials
Top Sponsor
VA Office of Research and Development
3 trials
Dominant Phase
NA
69 of 104 sampled
Pipeline Overview
Phase Distribution
NA
69
Early I
3
Phase 1
5
Phase 2
6
Phase 3
1
Other
20
Therapeutic Modalities
DEVICE
55
BEHAVIORAL
52
OTHER
52
DRUG
30
DIAGNOSTIC_TEST
14
PROCEDURE
7
COMBINATION_PRODUCT
3
BIOLOGICAL
2
Recruiting vs. Completed (2yr)
Recruiting
315
Completed
147
Competitive Landscape
Sponsor Classification
12%
88%
FED (3)
OTHER (22)
Top Sponsors
SponsorTrialsClass
VA Office of Research and Development3FED
University of Texas Southwestern Medical Center3OTHER
St. Jude Children's Research Hospital2OTHER
Joint Authority for Päijät-Häme Social and Health Care2OTHER
Riphah International University2OTHER
Istituti Clinici Scientifici Maugeri SpA2OTHER
Universita di Verona2OTHER
University of Florida2OTHER
Aarhus University Hospital1OTHER
Istanbul Medipol University Hospital1OTHER
Universitätsklinikum Hamburg-Eppendorf1OTHER
Ankara Yildirim Beyazıt University1OTHER
Mclean Hospital1OTHER
University of Illinois at Chicago1OTHER
Singapore Institute of Technology1OTHER
Geographic Distribution
Top U.S. States by Trial Density
StateTrialsTop City
Texas17Dallas
Florida10Orlando
California9San Diego
Massachusetts6Boston
Tennessee6Memphis
New York6New York
Minnesota4Minneapolis
Oregon3Portland
Colorado3Denver
Ohio3Cincinnati
Washington3Seattle
Illinois2Chicago
Michigan2Ann Arbor
Utah2Salt Lake City
Alabama2Birmingham
District of Columbia2Washington D.C.
Maryland2Columbia
Pennsylvania2Philadelphia
Virginia2Fairfax
Georgia1Augusta
Expansion Intelligence
+15650%
Discovery lift — trials found by semantic expansion that exact-match search misses entirely. This is the gap competitors don't see.
3
Exact
1
Parent
2
Region
3
Related
3
Comorbid
3
Therapeutic
Top Expansion Terms
  • cerebellar disorder Parent
  • cerebellar Region
  • posterior fossa Region
  • cerebellar ataxia Related
  • cerebellar mutism Related
  • posterior fossa syndrome Related
  • executive dysfunction Comorbid
  • visuospatial impairment Comorbid
  • affect dysregulation Comorbid
  • cerebellar stimulation Therapeutic

These terms are curated from clinical literature — not generated by a language model. Each captures trials that use variant nomenclature for the same underlying condition or therapeutic area.

Key Findings
What This Landscape Means for cerebellar cognitive affective syndrome
high
Standard searches miss 15650% of relevant trials for cerebellar cognitive affective syndrome — semantic expansion across related conditions and therapeutic approaches is essential for complete landscape visibility.
313 additional trials found via expansion vs 2 exact matches
high
Phase 2 volume (6) significantly exceeds Phase 3 (1), indicating a pipeline bottleneck — most candidates are 2-4 years from potential approval.
Phase 2/Phase 3 ratio: 6.0x
Next Steps
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Top Recruiting Trials
20 actively recruiting studies
RESET-BRAIN: REhabilitation of SleEp and CogniTive Impairment in BReast Cancer Survivors Using an App-based Intervention
Aarhus University Hospital n=84 Aarhus University Hospital Aarhus N
Intervention BEHAVIORAL: Cognitive Behavioral Therapy for Insomnia (CBT-I) — CBT-I is a multi-component intervention consisting of sleep restriction, stimulus control therapy, relaxation therapy, c...
Eligibility Ages 18 Years, FEMALE only
Contact Ali Amidi · +4587165305 · ali@psy.au.dk
Improving Cognitive Rehabilitation Outcomes
VA Office of Research and Development n=144 VA San Diego Healthcare System, San Diego, CA San Diego, California
Intervention DEVICE: CCT+MBLT — Compensatory Cognitive Training + Morning Bright Light Therapy (Aurora LightPad)
Eligibility Ages 18 Years
Contact Michelle Z Schy · (858) 255-4368 · michelle.schy@va.gov
Effects of Comprehensive Community Support Programs on Cognitive Function and Quality of Life in Older Adults
Istanbul Medipol University Hospital n=120 Vefahane Life Center, Bagcilar Municipality Istanbul, Bagcılar
Intervention BEHAVIORAL: Multidomain Community Support Program — Participants in the exposure group will attend multidomain community-based activities and supportive services provided a...
Eligibility Ages 60 Years
Contact Lütfü Hanoğlu · 905324868048 · lhanoglu@kure.com.tr
Cerebellar Transcranial Alternating Current Stimulation (tACS) to Modulate Parkinson's Disease Tremor
Universitätsklinikum Hamburg-Eppendorf n=10 Universitätsklinikum Hamburg-Eppendorf Hamburg, Free and Hanseatic City of Hamburg
Intervention DEVICE: Active-tACS — 30 seconds of closed-loop tACS at 2-4 mA, with 6 alternating phase alignments and 1-3 repetitions. Phase alignment is ad...
Eligibility Ages 18 Years
Contact Simone Zittel, Dr. med. · +49 40 7410 53770 · s.zittel-dirks@uke.de
COMPARISON OF BREATHING AND SUBOCCIPITAL RELEASE IN STROKE
Ankara Yildirim Beyazıt University n=54 Afyonkarahisar Health Sciences University Health Practice and Research Center Afyonkarahisar
Intervention OTHER: Breathing Exercise — Individuals assigned to Group 1 will receive deep breathing exercises in addition to the hospital's routine physiotherap...
Eligibility Ages 18 Years – 84 Years
Contact Zeynep Arikan · +905536655775 · zeynepcikar61@gmail.com
Using Transcranial Magnetic Stimulation (TMS) to Understand Hallucinations in Schizophrenia
Mclean Hospital n=68 McLean Hospital Belmont, Massachusetts
Intervention DEVICE: Repetitive Transcranial Magnetic Stimulation (rTMS) — rTMS is a technique of TMS that allows for selective external manipulation of neural activity in a non-invasive manner. ...
Eligibility Ages 18 Years – 55 Years
Contact Mark Halko, PhD · mhalko@mclean.harvard.edu
Cognitive Rehabilitation for Survivors of Childhood Medulloblastoma Using Real Time Hemodynamic Neurofeedback
St. Jude Children's Research Hospital n=40 St. Jude Children's Research Hospital Memphis, Tennessee
Intervention BEHAVIORAL: rt fMRI Neurofeedback (DLPFC) — Real time fMRI neurofeedback targeting the dorsolateral prefrontal cortex to train participants to increase DLPFC activi...
Eligibility Ages 10 Years – 25 Years
Contact Ranganatha Sitaram, ME, PhD · 866-278-5833 · referralinfo@stjude.org
Home Based Functional Balance Intervention for Multiple Sclerosis
University of Illinois at Chicago n=75 University of Illinois at Chicago Chicago, Illinois
Intervention BEHAVIORAL: Multicomponent balance intervention consisting of four components including dual-tasking, functional strength, vestibular and dynamic balance. — The Functional Balance Intervention (FBI) is a multicomponent, home based cognitive motor training program designed spec...
Eligibility Ages 40 Years – 90 Years
Contact Tanvi Bhatt, PhD · 3124139772 · tbhhat6@uic.edu
Stroke Rehabilitation Utilizing Therapeutical Methods Designed for Nature Environments
Joint Authority for Päijät-Häme Social and Health Care n=40 Joint Authority for Päijät-Häme Social and Health Care Lahti
Intervention BEHAVIORAL: Therapies in nature — Therapeutic tasks in nature specifically designed for the study
Eligibility Ages 18 Years
Contact Hanna Haveri, MD PhD · +358 3 81911 · hanna.haveri@paijatha.fi
Effect of Cognitive-Motor Dual-Task Training on Postural Stability and Functional Mobility in Stroke
Riphah International University n=28 Family Diagnostic Center Chak One Hundred Fifty-seven, Punjab Province
Intervention OTHER: Cognitive-motor dual-task training (CMDT) Group — Cognitive-motor dual-task training (CMDT) conducted three times weekly for 45-60 minutes with 10 repetitions each task o...
Eligibility Ages 40 Years – 75 Years
Contact Abrish H Abbasi, PhD* Rehab · 03155311799 · abrish.habib@riphah.edu.pk
NCT05535166 PHASE2
Molecular and Clinical Risk-Directed Therapy for Infants and Young Children With Newly Diagnosed Medulloblastoma
St. Jude Children's Research Hospital n=130 Lucille Packard Children's Hospital Stanford Palo Alto, California
Intervention PROCEDURE: Surgical resection — All participants enrolled will undergo surgical resection prior to treatment. The maximal resection that can be achieved...
Eligibility Ages 59 Months
Contact Tabatha E. Doyle, RN · 901-595-2544 · tabatha.doyle@stjude.org
Integrative Neuro-social Cognitive Strategy Programme for Instilling REcovery (INSPIRE) a Community-Based Cognitive Remediation Trial
Singapore Institute of Technology n=160 Anglican Care Center-Bukit Batok Singapore
Intervention BEHAVIORAL: Cognitive Remediation: Adapted Neuropsychological and Education Approach to Remediation (NEAR) — NEAR consists of computer-assisted cognitive exercises to restore cognitive functioning through rehearsal and strategy l...
Eligibility Ages 21 Years – 60 Years
Contact Bhing-Leet Tan, PhD · +6598422783 · bhingleet.tan@singaporetech.edu.sg
Cerebellar tDCS in Children With Autism Spectrum Disorder
University of Texas Southwestern Medical Center n=60 Children's Medical Center Dallas, Texas
Intervention DEVICE: tDCS — A current of 1 mA will be administered for 20 minutes of with either anodal or cathodal tDCS administration to the right...
Eligibility Ages 4 Years – 17 Years
Contact Peter Tsai, MD, PhD · 214-648-3577 · peter.tsai@utsouthwestern.edu
Posterior Fossa Intracranial Pressure (ICP) Measurement: Clinical Study
University of Valencia n=12 Hospital General Universitario de Valencia Valencia, Valencia
Intervention PROCEDURE: Posterior fossa intracranial pressure measurement — Measurement of posterior fossa pressure in an invasive way
Eligibility Ages 18 Years – 80 Years
Effect of Sensorimotor Training Versus Dual-task Training
Riphah International University n=54 DHQ Rajanpur Rajanpur, Punjab Province
Intervention OTHER: Sensorimotor Training — Somatosensory Training(SMT), for 30 minutes, thrice a week for 8 weeks. Warm-up and cool down will be given.
Eligibility Ages 40 Years – 60 Years
Contact Imran Amjad · +923324490125 · imran.amjad@riphah.edu.pk
Integrative Adolescence Research Programme (IARP)
Institute for Human Development and Potential (IHDP), Singapore n=1200 A*STAR Institute for Human Development and Potential (IHDP) Singapore, Singapore
Intervention OTHER: No intervention — No intervention
Eligibility Ages 13 Years – 15 Years
Contact Janet Lim · 88546302 · janet_lim@sics.a-star.edu.sg
Comparison of Vestibular and Dual-Task Rehabilitation in Parkinson's Disease
Marmara University n=45 Marmara University Istanbul, Maltepe
Intervention OTHER: Vestibular Rehabilitation — Vestibular exercises will consist of static and dynamic balance exercises, VOR and eye movement training, central balanc...
Eligibility Ages 40 Years – 75 Years
Contact Ezgi Eryıldız, PhD (c) · +905071180878 · fzt.ezgigul@gmail.com
Biomarker Research in Inherited Movement Disorders
Assistance Publique - Hôpitaux de Paris n=4000 Hôpital Pitié Salpetrière Paris
Intervention OTHER: Clinical follow-up — Clinical Follow-up: demographic data and history, * Retrospective interview (collection of data useful for genetic stu...
Eligibility Ages 7 Years
Contact Alexandra DURR, PUPH · 142161347 · alexandra.durr@aphp.fr
Registry and Natural History Study for Progressive Myoclonus Epilepsy Type 1 (EPM1)
Boston Children's Hospital n=200 Boston Childrens Hospital Boston, Massachusetts
Contact Darius Ebrahimi-Fakhari, MD, PhD. · 617-355-0097 · movementdisorders@childrens.harvard.edu
Cognitive Recovery Via Sensor-based Robotic Upper Limb Rehabilitation in Neurological Disorders
IRCCS Centro Neurolesi Bonino Pulejo n=189 IRCCS Centro Neurolesi Bonino-Pulejo Messina, Maine
Intervention DEVICE: Sensor-Based Robotic Rehabilitation with Cognitive Tasks (SBRR) — Participants receive upper limb rehabilitation using sensor-based robotic devices (e.g., Motore, Armeo Senso, Hand Tutor...
Eligibility Ages 18 Years – 75 Years
Contact Désirée Latella · +393458747117 · desiree.latella@ircssme.it