TrialFinder  /  Landscape Report CEREBELLAR MUTISM  ·  2026-10-26 Revasser  /  revasserkernel.com
Landscape Report TrialFinder
SOURCE  ClinicalTrials.gov API v2
GENERATED  2026-10-26
VERSION  v1
SAMPLE  100 of 494 studies

cerebellar mutism

The cerebellar mutism clinical trial landscape includes 494 actively recruiting trials. Semantic expansion identified 493 additional trials beyond exact-match search, representing a 49300% discovery lift across related conditions and therapeutic approaches.

Recruiting
494
active trials
Expansion Lift
+49300%
493 additional trials
Top Sponsor
Assistance Publique - Hôpitaux de Paris
3 trials
Dominant Phase
NA
53 of 106 sampled
Pipeline Overview
Phase Distribution
NA
53
Early I
4
Phase 1
12
Phase 2
12
Phase 3
2
Other
23
Therapeutic Modalities
DRUG
47
DIAGNOSTIC_TEST
43
BEHAVIORAL
42
DEVICE
40
OTHER
28
PROCEDURE
14
RADIATION
8
BIOLOGICAL
3
Recruiting vs. Completed (2yr)
Recruiting
494
Completed
194
Competitive Landscape
Sponsor Classification
100%
OTHER (30)
Top Sponsors
SponsorTrialsClass
Assistance Publique - Hôpitaux de Paris3OTHER
Institut Claudius Regaud2OTHER
Johns Hopkins University2OTHER
Medical College of Wisconsin2OTHER
St. Jude Children's Research Hospital2OTHER
Icahn School of Medicine at Mount Sinai2OTHER
University of Texas Southwestern Medical Center2OTHER
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins2OTHER
Syracuse University2OTHER
Emory University2OTHER
NYU Langone Health2OTHER
Teachers College, Columbia University2OTHER
Meyer Children's Hospital IRCCS2OTHER
Tata Memorial Centre2OTHER
Fundación de investigación HM1OTHER
Geographic Distribution
Top U.S. States by Trial Density
StateTrialsTop City
New York21New York
Texas20Dallas
California18San Francisco
Florida13Orlando
Massachusetts10Boston
Georgia8Atlanta
North Carolina8Durham
Michigan7Ann Arbor
New Jersey7New Brunswick
Ohio7Cleveland
Maryland6Baltimore
District of Columbia6Washington D.C.
Wisconsin5Milwaukee
Tennessee5Memphis
Missouri5St Louis
Illinois5Chicago
South Carolina4Columbia
Minnesota4Minneapolis
Washington4Seattle
Pennsylvania4Plymouth Meeting
Expansion Intelligence
+49300%
Discovery lift — trials found by semantic expansion that exact-match search misses entirely. This is the gap competitors don't see.
3
Exact
1
Parent
2
Region
3
Related
3
Comorbid
2
Therapeutic
Top Expansion Terms
  • posterior fossa syndrome Parent
  • cerebellar Region
  • posterior fossa Region
  • medulloblastoma Related
  • cerebellar tumor Related
  • pediatric brain tumor Related
  • mutism Comorbid
  • ataxia Comorbid
  • emotional lability Comorbid
  • speech therapy Therapeutic

These terms are curated from clinical literature — not generated by a language model. Each captures trials that use variant nomenclature for the same underlying condition or therapeutic area.

Key Findings
What This Landscape Means for cerebellar mutism
high
Standard searches miss 49300% of relevant trials for cerebellar mutism — semantic expansion across related conditions and therapeutic approaches is essential for complete landscape visibility.
493 additional trials found via expansion vs 1 exact matches
high
Phase 2 volume (12) significantly exceeds Phase 3 (2), indicating a pipeline bottleneck — most candidates are 2-4 years from potential approval.
Phase 2/Phase 3 ratio: 6.0x
Next Steps
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Top Recruiting Trials
20 actively recruiting studies
Evaluation of the Interest of a Video-assisted Remote Speech Therapy Consultation in Patients With ORL Cancer (TELE ORTHOPHONIE)
Institut Claudius Regaud n=105 Institut Universitaire du Cancer de Toulouse - Oncopole Toulouse
Intervention OTHER: Patient managed at the IUCT-O and by a private speech therapist (near the patient's home). — Each patient included will have a video-assisted remote speech therapy consultation with a private speech therapist (nea...
Eligibility Ages 18 Years
Contact Jérôme SARINI · 05 31 15 60 16 · sarini.jerome@iuct-oncopole.fr
NCT06607692 PHASE1, PHASE2
Study in Children and Adolescents of 177Lu-DOTATATE (Lutathera®) Combined With the PARP Inhibitor Olaparib for the Treatment of Recurrent or Relapsed Solid Tumours Expressing Somatostatin Receptor (SSTR) (LuPARPed).
Fundación de investigación HM n=25 HM Monteprincipe Boadilla del Monte, Madrid
Intervention DRUG: Olaparib; 177Lu-DOTATATE — 7Lu-DOTATATE will be administered intravenously, on day 1, every 8 weeks, at a fixed dose of 200 mCi (7.4 GBq) for child...
Eligibility Ages 3 Years
Contact Marta Osuna Marco MD, Medical Degree · +34 917 08 99 35 · marta.osuna@startmadrid.com
NCT03843463 PHASE2
Escitalopram and Language Intervention for Subacute Aphasia
Johns Hopkins University n=88 Johns Hopkins School of Medicine Baltimore, Maryland
Intervention DRUG: Escitalopram 10mg — Escitalopram tablet
Eligibility Ages 18 Years – 99 Years
Contact Argye Hillis-Trupe, MD · (410) 614-2381 · argye@jhmi.edu
Design and Implementation of a Carer Aromatherapy Training (CAT) Program for Children With Global Developmental Delay in Hong Kong: A Mixed Qualitative Study Using the COM-B Framework
Hong Kong Metropolitan University n=30 Hong Kong Metropolitan University Hong Kong
Intervention OTHER: Carer Aromatherapy Training (CAT) program and home massage with massage oil with the mixture of Petitgrain Mandarin (Citrus reticulate) essential oil and fractionated coconut oil — Carer Aromatherapy Training (CAT) program Following participants' consent to participate, an 8-hour face-to-face trainin...
Eligibility Ages 18 Years
Contact Sze Ki Veronica LAI, Dr · 85239708737 · sklai@hkmu.edu.hk
Characterization of Dysmorphology in Subjects With Creatine Transporter Deficiency
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) n=30 National Institutes of Health Clinical Center Bethesda, Maryland
Eligibility Ages 2 Years – 40 Years, MALE only
Contact Derek M Alexander · (301) 827-0387 · derek.alexander@nih.gov
Stimulating the Aging Brain Using Brain and Sensory Stimulation
Medical College of Wisconsin n=20 Medical College of Wisconsin Milwaukee, Wisconsin
Intervention DEVICE: tACS or multisensory stimulation — Active or sham tACS Light and/or sound flickers
Eligibility Ages 45 Years
Contact Sidney Schoenrock, MA · 414-955-7579 · sschoenrock@mcw.edu
Analysis of Parental Support in Families Using the LENA After Early Cochlear Implantation
Assistance Publique - Hôpitaux de Paris n=30 Hôpital Necker-Enfants Malades Paris
Intervention OTHER: LENA tool: Language ENvironment Analysis — Recording of the language environment of the child at home, in daily environment, with the LENA. The parameters recorde...
Eligibility Ages 11 Months – 21 Months
Contact Clara LEGENDRE, speech therapist · 1 71 39 67 96 · clara.legendre@aphp.fr
Post-market Evaluation of the Transition From the Baha Connect System to the Osia System in Adult Bone Conduction Implant Recipients
Cochlear n=20 Royal National Ear, Nose and Throat and Eastman Dental Hospitals London
Intervention DEVICE: Cochlear™ Osia® System — The Osia System consists of the OSI300 Implant, Osia 2 Sound Processor, Osia 2 Sound Processor Magnets, Osia 2 Sound Pro...
Eligibility Ages 18 Years
Contact PRS Specialist · +61 2 9428 6555 · cltd-prs-admin@cochlear.com
Cerebellar Transcranial Alternating Current Stimulation (tACS) to Modulate Parkinson's Disease Tremor
Universitätsklinikum Hamburg-Eppendorf n=10 Universitätsklinikum Hamburg-Eppendorf Hamburg, Free and Hanseatic City of Hamburg
Intervention DEVICE: Active-tACS — 30 seconds of closed-loop tACS at 2-4 mA, with 6 alternating phase alignments and 1-3 repetitions. Phase alignment is ad...
Eligibility Ages 18 Years
Contact Simone Zittel, Dr. med. · +49 40 7410 53770 · s.zittel-dirks@uke.de
Using Transcranial Magnetic Stimulation (TMS) to Understand Hallucinations in Schizophrenia
Mclean Hospital n=68 McLean Hospital Belmont, Massachusetts
Intervention DEVICE: Repetitive Transcranial Magnetic Stimulation (rTMS) — rTMS is a technique of TMS that allows for selective external manipulation of neural activity in a non-invasive manner. ...
Eligibility Ages 18 Years – 55 Years
Contact Mark Halko, PhD · mhalko@mclean.harvard.edu
Cognitive Rehabilitation for Survivors of Childhood Medulloblastoma Using Real Time Hemodynamic Neurofeedback
St. Jude Children's Research Hospital n=40 St. Jude Children's Research Hospital Memphis, Tennessee
Intervention BEHAVIORAL: rt fMRI Neurofeedback (DLPFC) — Real time fMRI neurofeedback targeting the dorsolateral prefrontal cortex to train participants to increase DLPFC activi...
Eligibility Ages 10 Years – 25 Years
Contact Ranganatha Sitaram, ME, PhD · 866-278-5833 · referralinfo@stjude.org
FOXP1 Syndrome: The Seaver Autism Center for Research and Treatment is Characterizing FOXP1-related Neurodevelopmental Disorders Using Genetic, Medical, and Neuropsychological Measures.
Icahn School of Medicine at Mount Sinai n=50 The Seaver Autism Center for Research and Treatment New York, New York
Eligibility Ages 2 Years
Contact Seaver Autism Center · 212-241-0961 · TheSeaverCenter@mssm.edu
Understanding Cognitive-Academic Bidirectionality in Math Learning Disabilities
Vanderbilt University n=300 Vanderbilt University Nashville, Tennessee
Intervention BEHAVIORAL: Coordinated Treatment — Coordinated Treatment provides 15 weeks (3 35-minute sessions per week) of intervention. Each session comprises 2 compon...
Eligibility Ages 6 Years – 8 Years
Contact Caitlin F. Craddock, B.A. · 615-491-1829 · c.f.craddock@vanderbilt.edu
NCT05535166 PHASE2
Molecular and Clinical Risk-Directed Therapy for Infants and Young Children With Newly Diagnosed Medulloblastoma
St. Jude Children's Research Hospital n=130 Lucille Packard Children's Hospital Stanford Palo Alto, California
Intervention PROCEDURE: Surgical resection — All participants enrolled will undergo surgical resection prior to treatment. The maximal resection that can be achieved...
Eligibility Ages 59 Months
Contact Tabatha E. Doyle, RN · 901-595-2544 · tabatha.doyle@stjude.org
Cerebellar tDCS in Children With Autism Spectrum Disorder
University of Texas Southwestern Medical Center n=60 Children's Medical Center Dallas, Texas
Intervention DEVICE: tDCS — A current of 1 mA will be administered for 20 minutes of with either anodal or cathodal tDCS administration to the right...
Eligibility Ages 4 Years – 17 Years
Contact Peter Tsai, MD, PhD · 214-648-3577 · peter.tsai@utsouthwestern.edu
Posterior Fossa Intracranial Pressure (ICP) Measurement: Clinical Study
University of Valencia n=12 Hospital General Universitario de Valencia Valencia, Valencia
Intervention PROCEDURE: Posterior fossa intracranial pressure measurement — Measurement of posterior fossa pressure in an invasive way
Eligibility Ages 18 Years – 80 Years
Transcutaneous Vagus Nerve Stimulation in Aphasia After Stroke
Sheffield Teaching Hospitals NHS Foundation Trust n=36 Sheffield Teaching Hospitals NHS Foundation Trust Sheffield
Intervention DEVICE: Transcutaneous Vagus Nerve Stimulation — Transcutaneous auricular vagus nerve stimulation using the Nurosym (Parasym Ltd) device. Stimulation parameters: Pulse...
Eligibility Ages 18 Years
Contact Dr Ali Ali · 01142159114 · ali.ali@sheffield.ac.uk
Transcranial Alternating Current Stimulation (tACS) in Aphasia
Medical College of Wisconsin n=50 Medical College of Wisconsin Milwaukee, Wisconsin
Intervention DEVICE: tACS — Active or Sham tACS will be applied.
Eligibility Ages 18 Years – 85 Years
Contact Sidney Schoenrock, MA · 414-955-7579 · sschoenrock@mcw.edu
Cognitive Outcomes After Brain Substructure-informed Radiation Planning in Pediatric Patients
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins n=338 Sibley Memorial Hospital Washington D.C., District of Columbia
Intervention RADIATION: substructure informed planning — Radiation Therapy with substructure informed planning determined by the PI.
Eligibility Ages 1 Year – 26 Years
Contact Sahaja Acharya, MD · 202-537-4788 · sachary7@jhmi.edu
Biomarker Research in Inherited Movement Disorders
Assistance Publique - Hôpitaux de Paris n=4000 Hôpital Pitié Salpetrière Paris
Intervention OTHER: Clinical follow-up — Clinical Follow-up: demographic data and history, * Retrospective interview (collection of data useful for genetic stu...
Eligibility Ages 7 Years
Contact Alexandra DURR, PUPH · 142161347 · alexandra.durr@aphp.fr