TrialFinder  /  Landscape Report CEREBELLAR MUTISM  ·  2026-09-02 Revasser  /  revasserkernel.com
Landscape Report TrialFinder
SOURCE  ClinicalTrials.gov API v2
GENERATED  2026-09-02
VERSION  v1
SAMPLE  100 of 490 studies

cerebellar mutism

The cerebellar mutism clinical trial landscape includes 490 actively recruiting trials. Semantic expansion identified 489 additional trials beyond exact-match search, representing a 48900% discovery lift across related conditions and therapeutic approaches.

Recruiting
490
active trials
Expansion Lift
+48900%
489 additional trials
Top Sponsor
Johns Hopkins University
5 trials
Dominant Phase
NA
64 of 104 sampled
Pipeline Overview
Phase Distribution
NA
64
Early I
3
Phase 1
12
Phase 2
8
Phase 4
1
Other
16
Therapeutic Modalities
DEVICE
58
BEHAVIORAL
48
OTHER
24
DRUG
21
PROCEDURE
7
DIAGNOSTIC_TEST
7
BIOLOGICAL
4
RADIATION
4
Recruiting vs. Completed (2yr)
Recruiting
490
Completed
188
Competitive Landscape
Sponsor Classification
94%
6%
OTHER (29)
INDUSTRY (2)
Top Sponsors
SponsorTrialsClass
Johns Hopkins University5OTHER
Medical College of Wisconsin3OTHER
Weill Medical College of Cornell University3OTHER
MGH Institute of Health Professions2OTHER
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins2OTHER
Syracuse University2OTHER
University of Texas at Austin2OTHER
University of Pittsburgh2OTHER
University of Texas Southwestern Medical Center2OTHER
University of Florida2OTHER
Biogen2INDUSTRY
Fondazione Don Carlo Gnocchi ETS1OTHER
Chinese University of Hong Kong1OTHER
University of Sheffield1OTHER
The Cleveland Clinic1OTHER
Geographic Distribution
Top U.S. States by Trial Density
StateTrialsTop City
Texas18Austin
New York12New York
Maryland11Baltimore
Florida10Gainesville
California9Los Angeles
Pennsylvania8Philadelphia
Massachusetts8Boston
District of Columbia6Washington D.C.
Ohio4Cleveland
New Jersey4Bloomfield
Tennessee4Nashville
Minnesota3Minneapolis
Wisconsin3Milwaukee
Georgia3Atlanta
Colorado3Denver
Missouri2St Louis
Michigan2Ann Arbor
Arizona2Tucson
Utah2West Valley City
Virginia2Fairfax
Expansion Intelligence
+48900%
Discovery lift — trials found by semantic expansion that exact-match search misses entirely. This is the gap competitors don't see.
3
Exact
1
Parent
2
Region
3
Related
3
Comorbid
2
Therapeutic
Top Expansion Terms
  • posterior fossa syndrome Parent
  • cerebellar Region
  • posterior fossa Region
  • medulloblastoma Related
  • cerebellar tumor Related
  • pediatric brain tumor Related
  • mutism Comorbid
  • ataxia Comorbid
  • emotional lability Comorbid
  • speech therapy Therapeutic

These terms are curated from clinical literature — not generated by a language model. Each captures trials that use variant nomenclature for the same underlying condition or therapeutic area.

Key Findings
What This Landscape Means for cerebellar mutism
high
Standard searches miss 48900% of relevant trials for cerebellar mutism — semantic expansion across related conditions and therapeutic approaches is essential for complete landscape visibility.
489 additional trials found via expansion vs 1 exact matches
Next Steps
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Top Recruiting Trials
20 actively recruiting studies
Outcomes of ICT Assistive Technology in RehabiliTAtIoN Pathways
Fondazione Don Carlo Gnocchi ETS n=50 IRCCS Fondazione Don Carlo Gnocchi ONLUS Milan, MI
Intervention OTHER: scales and questionnaire administration — evaluation of the quality of prosthetic intervention, verification of the adequacy of assistive devices, and outcomes me...
Contact Claudia Salatino · +39-0240308283 · csalatino@dongnocchi.it
Hong Kong Spinocerebellar Ataxias Registry
Chinese University of Hong Kong n=300 Prince of Wales Hospital Hong Kong, Shatin
Intervention OTHER: no intervention — No intervention but clinical assessement for all recruited subjects
Eligibility Ages 18 Years – 90 Years
Contact Anne YY CHAN · (852) 3505 1855 · yychananne@gmail.com
Effectiveness of CAT-GSH for Returning Patients
University of Sheffield n=100 Tameside and Glossop NHS Talking Therapies Service Ashton-under-Lyne
Intervention BEHAVIORAL: Cognitive analytic therapy guided self-help (CAT-GSH) — Six session CAT-GSH treatment
Eligibility Ages 16 Years
Contact Andrew J Laphan · 01142226650 · alaphan1@sheffield.ac.uk
Efficacy of Low-intensity Shockwave vs Radial Wave for Treatment of Erectile Dysfunction and Pelvic Pain
The Cleveland Clinic n=186 Cleveland Clinic Foundation Cleveland, Ohio
Intervention DEVICE: Focused shockwave — Storz Duolith SD-1 (Storz Medical, Tagerwilen, Switzerland)
Eligibility Ages 40 Years, MALE only
Contact Petar Bajic · 216-444-1231 · bajicp@ccf.org
Targeted TDCS to Enhance Speech-Language Treatment Outcome in Persons With Chronic Post-Stroke Aphasia.
University of New Mexico n=50 University of New Mexico Center for Brain Recovery and Repair Albuquerque, New Mexico
Intervention DEVICE: Active Comparator: Experimental: Active cathodal tDCS + language training — Cathodal tDCS raises neuronal membrane potentials, leading to decreased probability of depolarization from incoming stim...
Eligibility Ages 25 Years – 85 Years
Contact Jessica Richardson, Ph.D. · 505 277-1765 · jdrichardson@unm.edu
pBFS Guided aiTBS Over Language Network for ASD Child
Beijing Changping Tianhe Research Institute of Brain Science n=150 Peking University Sixth Hospital Beijing
Intervention DEVICE: active iTBS — Participants will undergo three iTBS sessions per day, with 1800 pulses per session, over a 12-week period. Individualiz...
Eligibility Ages 3 Years – 6 Years
Contact Xinyu Duan · 13691009590 · xinyu.duan@neuralgalaxy.com
Hospital and Home Rehabilitation Based on Social Care Robotics and Artificial Intelligence for Pediatric Patients
Inrobics Social Robotics, S.L. n=30 Hospital Infantil Universitario Niño Jesús Madrid, Madrid
Intervention DEVICE: Robot-assisted, gamified pediatric upper-limb rehabilitation (hybrid clinic + home program) — The intervention is a hybrid pediatric rehabilitation program delivered through a socially assistive robotics-based virt...
Eligibility Ages 7 Years – 16 Years
Contact José Carlos Pulido, Engineering · +34 630423231 · jcpulido@inrobics.com
Cycling-Based Priming Coordination Training for Enhancing Ataxia Recovery and Brain Plasticity
Chang Gung University n=40 Chang Gung University Taoyuan
Intervention PROCEDURE: Cycling Training — Cycling combined with priming strategies to enhance motor learning tasks. Each session will last for 15 minutes, conduct...
Eligibility Ages 18 Years
Cerebellar Stimulation for Aphasia Rehabilitation
Johns Hopkins University n=60 Johns Hopkins Hospital Baltimore, Maryland
Intervention DEVICE: Cathodal Cerebellar tDCS — 2 mA of cathodal tDCS is induced between two 5cm X 5cm saline soaked sponges where the cathode sponge is placed on the r...
Eligibility Ages 18 Years – 99 Years
Contact Rajani Sebastian, PhD · 410-502-2445 · rsebast3@jhmi.edu
NCT05717712 PHASE1
Oncolytic Virus Ad-TD-nsIL12 for Primary Pediatric Diffuse Intrinsic Pontine Glioma
Capital Medical University n=18 Sanbo Brain Hospital, Capital Medical University Beijing, Beijing Municipality
Intervention BIOLOGICAL: Ad-TD-nsIL12 — After stereotactic biopsy, the Ommaya reservoir will be inserted through the biopsy channel and two injections of Ad-TD-...
Eligibility Ages 1 Year – 18 Years
Contact Xiao Qian, Dr. · 18020295435 · ryan521q@sina.com
Individualized Treatment Plan in Children and Young Adults With Relapsed Medulloblastoma and Ependymoma
University of California, San Francisco n=74 Children's Hospital of Los Angeles Los Angeles, California
Intervention OTHER: Specialized Tumor Board Treatment Plan — Specialized Treatment Plan of up to four FDA approved drugs based on participant's screening results will be assigned by...
Eligibility Ages 12 Months – 39 Years
Contact PNOC Operation Office · 415-502-1600 · PNOC027@ucsf.edu
Connect-One: Early Feasibility Study of Connexus® Brain-Computer Interface (BCI)
Paradromics n=2 University of California, Davis Sacramento, California
Intervention DEVICE: Connexus Brain-Computer Interface — The Connexus Brain Computer Interface is an implantable brain-computer interface.
Eligibility Ages 22 Years – 75 Years
Contact Paradromics Clinical Team · (512) 559 4120 · clinical-team@paradromics.com
Deep Anterior Cerebellar Stimulation in Treatment of Poststroke Spasticity and Motor Function Impairment.
Jan Biziel University Hospital No 2 in Bydgoszcz n=12 Department of Neurosurgery and Neurology University Hospital nr 2 Collegium Medicum Nicolaus Copernicus University Bydgoszcz
Intervention PROCEDURE: Deep brain stimulation electrode implantation with an electrode target in the dentate nucleus — The intervention will involve implantation of a directional electrode with a target in the dentate nucleus of the cerebe...
Eligibility Ages 18 Years
Contact Paweł Sokal, Ph.D. · +48600954415 · pawel.sokal@cm.umk.pl
NCT06161519 PHASE1, PHASE2
PLX038 in Primary Central Nervous System Tumors Containing MYC or MYCN Amplifications
National Cancer Institute (NCI) n=146 National Institutes of Health Clinical Center Bethesda, Maryland
Intervention DRUG: PLX038 — PLX038 is given intravenously (IV) at the assigned dose level over about 1 hour on day 1 of each 21-day cycle
Eligibility Ages 18 Years – 120 Years
Contact NCI NOB Referral Group · (866) 251-9686 · ncinobreferrals@mail.nih.gov
NCT06540989 EARLY_PHASE1
Noise-augmented Automatic Speech Recognition for Speech Treatment in Parkinson's Disease
Teachers College, Columbia University n=42 Teachers College, Columbia University New York, New York
Intervention BEHAVIORAL: Immediate treatment — Participants will access a web-based app using their phone to record 100 sentences every treatment session. Noise-augmen...
Eligibility Ages 50 Years – 80 Years
Contact Gemma Moya-Galé, Ph.D. · 212-678-3323 · gm2446@tc.columbia.edu
Speech Treatment for Minimally Verbal Children With ASD and CAS
MGH Institute of Health Professions n=20 MGH Institute of Health Professions Boston, Massachusetts
Intervention BEHAVIORAL: CAS Treatment for Minimally Verbal Children with Autism — Treatment involves principles of motor learning embedded in a naturalistic developmental milieu
Eligibility Ages 5 Years – 18 Years
Contact Karen V Chenausky, Ph.D. · 617-726-2405 · kvchenausky@mghihp.edu
Cognitive Outcomes After Brain Substructure-informed Radiation Planning in Pediatric Patients
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins n=338 Sibley Memorial Hospital Washington D.C., District of Columbia
Intervention RADIATION: substructure informed planning — Radiation Therapy with substructure informed planning determined by the PI.
Eligibility Ages 1 Year – 26 Years
Contact Sahaja Acharya, MD · 202-537-4788 · sachary7@jhmi.edu
Intervention for Communication Quality of Life in Primary Progressive Aphasia
Maya Henry n=30 University of Texas Austin, Texas
Intervention BEHAVIORAL: Multicomponent Lexical Retrieval Cascade Training — In person or via teletherapy: A multi-component treatment incorporating elements of restitutive, compensatory, and care-...
Eligibility Ages 40 Years
Contact Henry Lab Research Coordinator · 512-471-3420 · aphasialab@austin.utexas.edu
Irradiation in Paediatrics: Neurocognition, Neuroimaging and Evaluation of Memory and Attention
Institut Claudius Regaud n=130 CHU Angers Angers
Intervention OTHER: Neuropsychological assessments: — Several neuropsychological assessments were carried out during the study (at inclusion and 2 years after inclusion), con...
Eligibility Ages 6 Years – 14 Years
Contact Anne LAPRIE · 05 31 15 54 43 · laprie.anne@iuct-oncopole.fr
Ecological Momentary Intervention for Post-Stroke Anomia
Northeastern University n=24 Northeastern University Boston, Massachusetts
Intervention BEHAVIORAL: Semantic Feature Ecological Momentary Intervention — If answered, each prompt will correspond to a single picture naming training trial. The trial flow will include five ste...
Eligibility Ages 18 Years – 89 Years
Contact Erin L Meier, PhD · 617-373-7438 · e.meier@northeastern.edu