TrialFinder  /  Landscape Report DANDY-WALKER  ·  2026-09-03 Revasser  /  revasserkernel.com
Landscape Report TrialFinder
SOURCE  ClinicalTrials.gov API v2
GENERATED  2026-09-03
VERSION  v1
SAMPLE  100 of 438 studies

dandy-walker

The dandy-walker clinical trial landscape includes 438 actively recruiting trials. Semantic expansion identified 437 additional trials beyond exact-match search, representing a 43700% discovery lift across related conditions and therapeutic approaches.

Recruiting
438
active trials
Expansion Lift
+43700%
437 additional trials
Top Sponsor
Riphah International University
5 trials
Dominant Phase
NA
42 of 103 sampled
Pipeline Overview
Phase Distribution
NA
42
Early I
2
Phase 1
6
Phase 2
10
Phase 3
6
Phase 4
3
Other
34
Therapeutic Modalities
DRUG
36
DIAGNOSTIC_TEST
29
DEVICE
26
BEHAVIORAL
24
OTHER
22
BIOLOGICAL
17
PROCEDURE
8
GENETIC
4
Recruiting vs. Completed (2yr)
Recruiting
438
Completed
189
Competitive Landscape
Sponsor Classification
97%
3%
OTHER (28)
INDUSTRY (1)
Top Sponsors
SponsorTrialsClass
Riphah International University5OTHER
Hugo W. Moser Research Institute at Kennedy Krieger, Inc.3OTHER
IRCCS Eugenio Medea2OTHER
University of Florida2OTHER
Örebro University, Sweden2OTHER
Northwell Health2OTHER
Icahn School of Medicine at Mount Sinai2OTHER
University of Texas Southwestern Medical Center2OTHER
Centre Hospitalier Universitaire de Nice2OTHER
University of Colorado, Denver2OTHER
Simons Searchlight1OTHER
University of Nevada, Las Vegas1OTHER
Sanford Health1OTHER
Rocket Pharmaceuticals Inc.1INDUSTRY
Fundación Hospitalarias Betanzos1OTHER
Geographic Distribution
Top U.S. States by Trial Density
StateTrialsTop City
California32Los Angeles
Florida25Orlando
New York25New York
Texas25Houston
Nevada24Las Vegas
Michigan23Grand Rapids
Massachusetts15Boston
Pennsylvania15Philadelphia
Ohio15Cleveland
Maryland12Baltimore
Illinois12Chicago
New Jersey11New Brunswick
North Carolina10Durham
Missouri9St Louis
Tennessee8Nashville
Washington8Seattle
Georgia7Atlanta
Arizona6Phoenix
Colorado6Aurora
Alabama5Birmingham
Expansion Intelligence
+43700%
Discovery lift — trials found by semantic expansion that exact-match search misses entirely. This is the gap competitors don't see.
3
Exact
2
Parent
3
Region
3
Related
3
Comorbid
2
Therapeutic
Top Expansion Terms
  • cerebellar malformation Parent
  • posterior fossa malformation Parent
  • posterior fossa Region
  • cerebellar Region
  • fourth ventricle Region
  • hydrocephalus Related
  • agenesis of cerebellar vermis Related
  • cerebellar hypoplasia Related
  • developmental delay Comorbid
  • intellectual disability Comorbid

These terms are curated from clinical literature — not generated by a language model. Each captures trials that use variant nomenclature for the same underlying condition or therapeutic area.

Key Findings
What This Landscape Means for dandy-walker
high
Standard searches miss 43700% of relevant trials for dandy-walker — semantic expansion across related conditions and therapeutic approaches is essential for complete landscape visibility.
437 additional trials found via expansion vs 1 exact matches
high
6 Phase 3 trials indicate a maturing pipeline with near-term approval potential.
Phase 3 represents 6% of sampled trials
Next Steps
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Top Recruiting Trials
20 actively recruiting studies
Online Study of People Who Have Genetic Changes and Features of Autism: Simons Searchlight
Simons Searchlight n=100000 Boston Children's Hospital Boston, Massachusetts
Contact Simons Searchlight Study Coordinator · 855-329-5638 · coordinator@SimonsSearchlight.org
Efficacy of Stabilometric Platform to Improve Standing Balance in Patients With Friedreich's Ataxia
IRCCS Eugenio Medea n=24 Scientific Institute, IRCCS E. Medea, Department of Pieve di Soligo, Treviso, Italy Pieve di Soligo, Veneto
Intervention BEHAVIORAL: Balance training over stabilometric platform — The treatment using the stabilometric platform (a total of 20 sessions) generally includes an initial phase (approximate...
Eligibility Ages 14 Years
Contact Gabriella Paparella, Medical Degree · 00390438906330 · gabriella.paparella@lanostrafamiglia.it
Ergonomic Protocol for Competitive E-Sport Athletes
University of Nevada, Las Vegas n=12 University of Nevada, Las Vegas Las Vegas, Nevada
Intervention OTHER: Esports Ergonomic Protocol — The Esports Ergonomic Protocol is a six-week intervention designed to reduce the risk of repetitive strain injuries and ...
Eligibility Ages 18 Years
Contact Althea Rivera · (702) 215 1588 · rivera21@unlv.nevada.edu
Rare Disease Patient Registry & Natural History Study - Coordination of Rare Diseases at Sanford
Sanford Health n=20000 Sanford Health Sioux Falls, South Dakota
Contact CoRDS Team · 1-877-658-9192 · cords@sanfordhealth.org
NCT06092034 PHASE2
A Gene Therapy Study of RP-A501 in Male Patients With Danon Disease
Rocket Pharmaceuticals Inc. n=14 University of California, San Diego La Jolla, California
Intervention GENETIC: RP-A501 — RP-A501 is a gene therapy product consisting of a rAAV9 capsid containing the human LAMP2B transgene which will be admin...
Eligibility Ages 8 Years, MALE only
Contact Clinical Information · 646-627-0033 · clinicaltrials@rocketpharma.com
Interposed Nucleus aDBS for Ataxia
University of Florida n=5 Norman Fixel Institute for Neurological Diseases Gainesville, Florida
Intervention DEVICE: Deep Brain Stimulation — This device will be surgically implanted into the interposed nucleus of the cerebellum.
Eligibility Ages 21 Years – 89 Years
Contact Julia C Gonzalez, BA · (352) 265-0111 · Julia.Gonzalez@neurology.ufl.edu
Biomarkers in Friedreich's Ataxia
University of Florida n=203 University of Florida Gainesville, Florida
Eligibility Ages 6 Years – 70 Years
Contact Mackenzi Coker, M.S.CCC-SLP · 352-294-8754 · mcoker@peds.ufl.edu
Evaluation of CO-OP for Adolescents With Mild Intellectual Disability
Örebro University, Sweden n=60 Region Skåne Kristianstad, Skåne County
Intervention OTHER: The Cognitive Orientation to Daily Occupational Performance Approach — CO-OP is a client-centred, performance-based, problem-solving focused, occupation-focused and occupation-based intervent...
Eligibility Ages 13 Years – 17 Years
Contact Elin Widmark, MSc · +46108319064 · elin.widmark@oru.se
Falls In Spanish People With Intellectual Disabilities: Risk Factors And Predictive Equation. Falls.Di Study
Fundación Hospitalarias Betanzos n=600 Fundación Hospitalarias Betanzos Betanzos, A Coruña
Eligibility Ages 18 Years
Contact Noemi Dobaño García · +34 981770056 · noemialba.dobano@fundacionhospitalarias.org
Studying Childhood-onset Behavioral, Psychiatric, and Developmental Disorders
National Institute of Mental Health (NIMH) n=1000 National Institutes of Health Clinical Center Bethesda, Maryland
Eligibility Ages 30 Days – 99 Years
Contact Jessica M Vaughan, C.R.N.P. · (301) 435-7958 · jessica.vaughan@nih.gov
Use of a Digital Snapshot to Reduce Use of Restraints During Emergency Department Visits and Improve Experience of Care for PWIDD
Northwell Health n=1500 Cohen Children's Medical Center New Hyde Park, New York
Intervention OTHER: Always Uniquely Me mobile phone application — The app will allow the user to organize their healthcare information and personal needs which can help improve communica...
Eligibility Ages 18 Years
Contact Sophia Jan Division Chief, MD, MSHP · (516) 465-4377 · sjan1@northwell.edu
White Matter Distortion and Dementia Biomarkers in Normal Pressure Hydrocephalus (NPH)
Imperial College London n=100 Imperial College Healthcare NHS Trust London
Intervention PROCEDURE: Ventriculoperitoneal Shunt (VP) — VP Shunt surgery involves surgical insertion of a catheter (tube) to divert brain fluid from the cerebral ventricles to ...
Eligibility Ages 60 Years
Contact Chris Carswell · +44 20311 1234 · NPH@imperial.ac.uk
Early Intervention Based on Neonatal Crawling in Very Premature Infants at Risk For Neurodevelopmental Disorder
Marianne Barbu-Roth n=50 Hôpital Paris Saint-Joseph Paris
Intervention BEHAVIORAL: Crawling stimulation with a mini-skateboard (i.e. the crawliskate) — Consists of 8 weeks of daily training. Infants benefit from a 10 minutes session everyday at home with either a trained ...
Eligibility Ages 39 Weeks – 42 Weeks
Contact Marianne Barbu-Roth, PhD · 00336 18 61 09 15 · barburoth@gmail.com
Aerobic Exercise With and Without Low Calorie Diet on Adiposity and BMI of Down Syndrome
Riphah International University n=22 Jannat Arshad Lahore, Punjab Province
Intervention OTHER: Aerobic Exercise and Low Calorie Diet — Group A: Aerobic Exercise with Low calorie diet Group B: Aerobic Exercise without Low Calorie Diet
Eligibility Ages 8 Years – 16 Years
Contact Imran Amjad, PhD · 9233224390125 · imran.amjad@riphah.edu.pk
Evaluation of a Home-based Parenting Support Program: Parenting Young Children
Örebro University, Sweden n=60 Social Welfare Office Enköping
Intervention BEHAVIORAL: Parenting Young Children — PYC is a home-based intervention programme involving weekly, one-hour sessions over a period of at least six months. The...
Contact Tommie Forslund, PhD · +468163958 · tommie.forslund@psychology.su.se
Global Registry and Natural History Study for Mitochondrial Disorders
LMU Klinikum n=6000 Medical University Innsbruck, Department of Pediatrics Innsbruck
Contact Boriana Büchner, Dr. · +49 89 4400 · boriana.buechner@med.uni-muenchen.de
Development of IPS from Donated Somatic Cells of Patients with Neurological Diseases
Hadassah Medical Organization n=120 Hadassah Ein Kerem Jerusalem, Israel
Eligibility Ages 18 Years
Contact Benjamin E. Reubinoff, MD PhD · 011-972-2-677-4569 · benjaminr@ekmd.huji.ac.il
Effects of Modified Pilates on Improving Trunk Control and Balance in Children With Mild Intellectual Disability
Riphah International University n=40 Rising Sun Institute Lahore, Pinjab
Intervention OTHER: Modified Pilate Exercises — Modified Pilates exercises are gentle adaptations of traditional Pilates movements, designed to accommodate various fitn...
Eligibility Ages 6 Years – 12 Years
Contact IMRAN AMJAD, PhD · 33224390125 · imran.amjad@riphah.edu.pk
Clinical Course Of Disease In Participants With FA-CM
Lexeo Therapeutics n=65 University of California San Diego La Jolla, California
Eligibility Ages 6 Years
Contact Lexeo Clinical Trials · 212-547-9879 · clinicaltrials@lexeotx.com
Prevent Language Delays and Disorders Among Children of Caregivers With Substance Use Disorders With Community Groups and Individualized Services
University of Oregon n=244 Prevention Science Institute Eugene, Oregon
Intervention BEHAVIORAL: Comilia Group — Parents participate in six weekly 90-minute in-person groups led by a trained facilitator and offered in English or Span...
Eligibility Ages 18 Years
Contact Stephanie De Anda, PhD, CCC-SLP · 541-346-8530 · sdeanda@uoregon.edu