Top Recruiting Trials
20 actively recruiting studies
Global Real World Data in Patients With Advanced Thyroid Cancer on Standard of Care and Specialized Interventions- Registry of Oncologic Outcomes With Testing and Treatment.
M.D. Anderson Cancer Center
n=459
MD Anderson Cancer Center
Houston, Texas
Eligibility Ages 18 Years
Prospective Outcomes of Guided Equator Overdentures
Menoufia University
n=40
Faculty of Dentistry
Shibīn al Kawm
Intervention DEVICE: Fully guided static computer-assisted implant surgery (CAIS) for mandibular overdentures using Equator® attachments — Mandibular edentulism will be rehabilitated with implant-supported overdentures using a fully guided static computer-ass...
Eligibility Ages 40 Years – 70 Years
The Safety, Tolerability, and Pharmacokinetics of of SYH9017 in Chinese Participants With Overweight and Obesity
CSPC Baike (Shandong) Biopharmaceutical Co., Ltd.
n=66
Peking University Third Hospital
Beijing, Beijing Municipality
Intervention DRUG: SYH9017 — subcutaneous injection once time in SAD and four times in MAD
Eligibility Ages 18 Years – 60 Years
Does Abnormal Insulin Action in the Brain Underlie Cognitive and Metabolic Dysfunction in Schizophrenia
Centre for Addiction and Mental Health
n=20
Centre for Addiction and Mental Health
Toronto, Ontario
Intervention DRUG: Intranasal insulin — 160 IU insulin (Humalog) is administered intranasally using a metered spray bottle 15 minutes prior to the PET scan.
Eligibility Ages 17 Years – 45 Years
The Cardio-Metabolic Clinic
Odense University Hospital
n=1600
Cardiovascular Research Unit, Odense University Hospital - Svendborg
Svendborg, Region Syddanmark
Intervention OTHER: Cardio-Metabolic Clinic — The Cardio-Metabolic Clinic will adhere to a standardized evaluation and treatment program based on the latest treatment...
Eligibility Ages 19 Years
Transduction of Sympathetic Neural Activity in Human Obesity Without Hypertension
University of Kansas Medical Center
n=60
University of Kansas Medical Center
Kansas City, Kansas
Intervention DRUG: ascorbic acid — ascorbic acid
Eligibility Ages 18 Years – 79 Years
A Study of BMS-986504 Monotherapy and in Combination With Other Agents in Participants With Advanced and/or Metastatic Solid Tumors With Homozygous MTAP Deletion (MountainTAP-5)
Bristol-Myers Squibb
n=260
Local Institution - 0096
San Francisco, California
Intervention DRUG: BMS-986504 — Specified dose on specified days
Eligibility Ages 18 Years
Convenient Home Access for Routine Monitoring in Diabetes (Charm-D Study)
Tameside General Hospital
n=300
Tameside and Glossop Integrated Care NHS Foundation Trust
Ashton-under-Lyne, Lancs
Intervention DIAGNOSTIC_TEST: HbA1c test — Patients will be asked to have a HbA1c test in the clinic with a venous draw and then either fingerprick or upper arm dr...
Eligibility Ages 18 Years
Thyroxine Replacement Therapy After Lobectomy for Low-risk Papillary Thyroid Carcinoma
Cancer Institute and Hospital, Chinese Academy of Medical Sciences
n=140
Cancer Hospital, Chinese Academy of Medical Science
Beijing, Beijing Municipality
Intervention DRUG: Thyroxine — The treatment goal after lobectomy was to control TSH within the normal reference range (0.4-5 mU/L)
Eligibility Ages 18 Months – 70 Years
Natural Course of Initially Metabolic Healthy Obese Individuals (Healthy Obesity)?
ETH Zurich
n=300
dTIP / ETH Zürich
Baden
Eligibility Ages 18 Years – 60 Years
A Study of Radspherin® in Patients With Primary Advanced Epithelial Cancer, With Peritoneal Metastasis That Are Homologous Recombination Proficient Scheduled to Undergo Neoadjuvant Chemotherapy and Interval Debulking Surgery
Oncoinvent Solutions AS
n=114
Moffitt Cancer Center
Tampa, Florida
Intervention DRUG: Radspherin — Radspherin® suspension consists of bio-degradable calcium carbonate micro particles with the α-emitting radionuclide 224...
Eligibility Ages 18 Years, FEMALE only
"Perfect Heartio" Drink and Cardiovascular Health
The Perfect Series Sdn Bhd
n=55
UCSI University
Cheras, Kuala Lumpur
Intervention DIETARY_SUPPLEMENT: Perfect Heartio Drink — Perfect Heartio (PH) drink is a nutritional drink composed of diluted herbal extracts of TCM, including ginger, Glycyrrh...
Eligibility Ages 18 Years
Single-arm, Prospective Clinical Trial of Efficacy and Safety of Daphnetin Capsules Combined With TC Regimen for Targeted Maintenance Therapy After Initial Treatment of Stage III-IV Epithelial Ovarian Cancer (RO/R1)
The First Hospital of Jilin University
n=98
The First Hospital of Jilin University
Changchun, Jilin
Intervention DRUG: Daphne Extract Capsules — The combination of Ruixiangsu capsules with the TC regimen for targeted maintenance therapy in epithelial ovarian cancer
Eligibility Ages 18 Years – 75 Years, FEMALE only
Impact of Removable Cast Walker Design on Usability for Patients With Diabetic Foot Ulcers
Rosalind Franklin University of Medicine and Science
n=40
Rosalind Franklin University of Medicine and Science
North Chicago, Illinois
Intervention DEVICE: RCW design form — Tall RCW= a knee high removable cast walker with an offloading insole
Short RCW= an ankle high (extending up the leg ju...
Eligibility Ages 18 Years
Carotid Wall Texture as a Cardiovascular Risk Biomarker in Type 2 Diabetes Mellitus
Cardenal Herrera University
n=80
Francisco Javier Molina Payá
Elche, Alicante
Intervention DIAGNOSTIC_TEST: SCORE2 — Will classify individuals into four cardiovascular risk categories:
* For participants aged 50-69 years:
* Low-to-mo...
Eligibility Ages 40 Years – 69 Years
Effect of Artificial Sweetener (AFS) on Glucose Metabolism in Patients with Type 1 Diabetes (T1D)
McGill University Health Centre/Research Institute of the McGill University Health Centre
n=25
Center for Innovative Medicine, The Research Institute of the McGill University Health Centre
Montreal, Quebec
Intervention OTHER: Sweet taste perception with/without sweet taste blockade — In our study, we will use our four different novel flavored beverages, with and without a sweet taste blockade.
Eligibility Ages 18 Years – 45 Years
Decitabine and Selinexor in Combination to Reverse Drug Resistance With Standard Chemotherapy in Ovarian Cancer
Loyola University
n=40
Loyola University Medical Center
Maywood, Illinois
Intervention DRUG: Decitabine — Decitabine is classified as hypomethylation agents. It works by helping the bone marrow produce normal blood cells and b...
Eligibility Ages 18 Years
Metabolic Biomarkers in Thoracic Cancers
University of Texas Southwestern Medical Center
n=200
University of Texas Southwestern Medical Center
Dallas, Texas
Intervention PROCEDURE: Imaging Biomarkers — Want to see if using 13C-glucose helps in detecting cancer and deciding on a treatment plan.
Eligibility Ages 18 Years
To Evaluate the Efficacy and Safety of N-acetyl Cysteine Administration in Patients With Diabetic Retinopathy
Ain Shams University
n=76
National Institute of Diabetes and Endocrinology.
Cairo
Intervention DRUG: N Acetyl cysteine, 1200mg (high dose) — N-acetylcysteine (NAC), alternatively referred to as N-acetyl-L-cysteine, is an acetylated version of the amino acid L-c...
Eligibility Ages 18 Years – 70 Years
Study of the Effects of Time-Restricted Feeding on the Immune Function of Individuals With Obesity
Assistance Publique - Hôpitaux de Paris
n=24
HEGP - digestive surgery
Paris
Intervention OTHER: Time-restrictred feeding — Time-restricted feeding pattern consisting of an 8 h eating window (from 6-8 am to 14-16 pm) followed by a 16 h fasting ...
Eligibility Ages 18 Years – 64 Years, FEMALE only