Top Recruiting Trials
20 actively recruiting studies
Identifying Challenges to Healthy Aging in Persons With Human Immunodeficiency Virus (HIV) Age 50 and Older
Wake Forest University Health Sciences
n=100
Atrium Health Wake Forest Baptist
Winston-Salem, North Carolina
Intervention OTHER: Customized activity plan — Clients with identified challenges to successful aging (pre-frail or frail on screening) will be invited to develop an i...
Eligibility Ages 50 Years
Integration of Cognitive Processing Therapy and Relapse Prevention for Alcohol Use Disorder and PTSD
Texas A&M University
n=200
Medical University of South Carolina
Charleston, South Carolina
Intervention BEHAVIORAL: Cognitive Processing Therapy + Relapse Prevention — Cognitive-Behavioral Therapy that integrates Cognitive Processing Therapy for PTSD with Relapse Prevention for alcohol u...
Eligibility Ages 18 Years
iCBT for Seniors With Depression in Primary Care
Göteborg University
n=390
University of Gothenburg
Gothenburg
Intervention BEHAVIORAL: iCBT for depression — iCBT depression program with minimal therapist contact offered within 14 days from inclusion and with a duration of 10-1...
Eligibility Ages 65 Years
Characterizing Dopamine Receptor Binding in Treatment Resistant Depression
Unity Health Toronto
n=45
Unity Health Toronto
Toronto, Ontario
Intervention DIAGNOSTIC_TEST: PET scans — PET scans and PHNO scans
Eligibility Ages 25 Years – 55 Years
DOR/TDF/3TC Switch With M184V/I in People With Controlled HIV (Drive Off-Road)
University Hospital, Caen
n=32
CHU de Caen
Caen
Intervention DRUG: Doravirine/Lamivudine/Tenofovir Disoproxil Fumarate 100 MG-300 MG-300 MG Oral Tablet [DELSTRIGO] — Switch previous therapy with DOR/TDF/3TC
Eligibility Ages 18 Years
Personalized Ultrasonic Brain Stimulation for Depression (R61)
Brian Mickey
n=30
University of Utah
Salt Lake City, Utah
Intervention DEVICE: LTFUS to SCC — Low-intensity transcranial focused ultrasound delivered to subgenual cingulate cortex
Eligibility Ages 18 Years – 65 Years
COpenhagen Magnetic Personalized Accelerated Brain Circuit Therapy for Treatment Resistant Depression
Danish Research Centre for Magnetic Resonance
n=78
Centre of Neuropsychiatric Depression Research
Glostrup Municipality
Intervention DEVICE: MagVenture XP Orange Stimulator and active side of MagVenture COOL-B65 coil. — Intermittent theta burst stimulation (iTBS) targeting the left dorsolateral prefrontal cortex (DLPFC) will be administer...
Eligibility Ages 18 Years – 95 Years
Interleaved TMS-fMRI in Ultra-treatment Resistant Depression
Sunnybrook Health Sciences Centre
n=88
Sunnybrook Health Sciences Centre
Toronto, Ontario
Intervention DEVICE: rTMS — Accelerated iTBS treatment
Eligibility Ages 20 Years – 65 Years
Study of ABX-002 for the Adjunctive Treatment of Major Depressive Disorder (AMPLIFY)
Autobahn Therapeutics, Inc.
n=230
Autobahn Site #131
Birmingham, Alabama
Intervention DRUG: ABX-002 — ABX-002 oral solution in 1-mL cyclic olefin polymer prefilled syringes, taken on an empty stomach first thing in the mor...
Eligibility Ages 18 Years – 65 Years
Enhanced Mentor Mother Strategy for Pregnant and Postpartum Women Living With HIV
Indiana University
n=200
Burnt Forest Sub-District Hospital
Burnt Forest, Uasin Gishu County
Intervention BEHAVIORAL: Enhanced Mentor Mother Strategy — The enhanced Mentor Mother strategy introduces a structured approach to differentiated PMTCT support, led by trained pee...
Eligibility Ages 18 Years, FEMALE only
Intranasal Insulin for Treatment of Alcohol Use Disorder
Brown University
n=40
Brown University
Providence, Rhode Island
Intervention DRUG: Regular Human Insulin then Placebo — Insulin: 80 IU (administered intranasally) THEN Placebo: 0.9% saline solution (administered intranasally)
Eligibility Ages 21 Years
Prepping for The Talk: Helping Trusted Adults and Youth Talk About Sexual Health
Rhode Island Hospital
n=40
Rhode Island Hospital
Providence, Rhode Island
Intervention BEHAVIORAL: Intervention — Youth: interventionist-facilitated 1:1 conversation with the youth via videoconference that includes a) brief sexual hea...
Eligibility Ages 14 Years – 17 Years, MALE only
Internet-Delivered Cognitive Behaviour Therapy for PTSD Among Public Safety Personnel
University of Regina
n=300
Department of Psychology and Collaborative Centre for Justice and Safety
Regina, Saskatchewan
Intervention BEHAVIORAL: PSP PTSD Course — A tailored ICBT intervention designed to treat symptoms of PTSD will be delivered to public safety personnel. Clients wi...
Eligibility Ages 18 Years
B.R.A.I.N in People Living With HIV Study
University of Cape Town
n=43
Michael Mapongwana Community Health Clinic
Cape Town, Western Cape
Intervention BEHAVIORAL: Combined Cognitive Symptom Management and Rehabilitation Therapy (CogSMART) and BrainHQ© — The intervention combines Cognitive Symptom Management and Rehabilitation Therapy (CogSMART) and BrainHQ. This integrate...
Eligibility Ages 30 Years – 50 Years
Evaluation of Safety and Immunogenicity of Ad26.Mos4.HIV and CH505 TF chTrimer Combination in Healthy Adults
U.S. Army Medical Research and Development Command
n=78
Makerere University Walter Reed Project (MUWRP)
Kampala
Intervention BIOLOGICAL: Ad26.Mos4.HIV in CH505 TF chTrimer + ALFQ [Arm 1a] — Participants in Arm 1a will receive dose consistent injections (5x10\^10 vp/0.5 mL) of Ad26.Mos4.HIV in a 0.5 mL injecti...
Eligibility Ages 18 Years – 50 Years
A Study of Brenipatide in Adult Participants With Major Depressive Disorder
Eli Lilly and Company
n=1000
Accellacare - Moorpark
Moorpark, California
Intervention DRUG: Brenipatide — Administered SC
Eligibility Ages 18 Years – 75 Years
Dog Presence and Oxytocin on Trust Towards Therapists
Dr. Karin Hediger
n=176
University of Basel
Basel, Canton of Basel-City
Intervention DRUG: Oxytocin nasal spray — Syntocinon nose spray is usually applied in the context of labour and breast feeding. In this study, however, it will be...
Eligibility Ages 18 Years
Anxiety During Abstinence in AUD
Columbia University
n=60
Columbia University Irving Medical Center
New York, New York
Intervention DRUG: Disulfiram 250 mg — Disulfiram will be used in Participants with Alcohol Use Disorder only to facilitate abstinence.
Eligibility Ages 21 Years – 55 Years
Effectiveness of an Online Biopsychosocial Intervention to Improve Well-being and Mental Health During Pregnancy
University Rovira i Virgili
n=228
Centre d'Atenció Primària Sant Pere
Reus, Tarragona
Intervention OTHER: Biopsychosocial Cognitive Behavioral Intervention — The study intervention is based on a biopsychosocial approach (considers the interaction between: biological factors suc...
Eligibility Ages 18 Years, FEMALE only
Translation and Validation of the Limbs, Pain, Autonomy, Depression, Anxiety and Quality of Life Scales in Albanian
Universidad Católica San Antonio de Murcia
n=300
Jasemin Todri
Murcia, Murcia
Eligibility Ages 18 Years – 80 Years