Top Recruiting Trials
20 actively recruiting studies
Molecular and Clinical Risk-Directed Therapy for Infants and Young Children With Newly Diagnosed Medulloblastoma
St. Jude Children's Research Hospital
n=130
Lucille Packard Children's Hospital Stanford
Palo Alto, California
Intervention PROCEDURE: Surgical resection — All participants enrolled will undergo surgical resection prior to treatment. The maximal resection that can be achieved...
Eligibility Ages 59 Months
Natural History of Treated Neurocysticercosis and Long-Term Outcomes
National Institute of Allergy and Infectious Diseases (NIAID)
n=500
National Institutes of Health Clinical Center
Bethesda, Maryland
Eligibility Ages 3 Years – 99 Years
Longitudinal Measurements of Flow in Cerebrospinal Fluid Shunts With a Wireless Thermal Anisotropy Measurement Device
Rhaeos, Inc.
n=130
Tampa Marriott Water Street
Tampa, Florida
Intervention DEVICE: Thermal Anisotropy Measurement Device — The study device is a non-invasive sensor that is placed on the study subject's skin overlying an existing implanted CSF...
Eligibility Ages 5 Years – 80 Years
Mechanisms of Brain-Heart Injury of Post-Intracranial Hemorrhage
Beijing Tiantan Hospital
n=1000
Beijing Tiantan Hospital Affiliated to Capital Medical University
Beijing, Beijing Municipality
Intervention DIAGNOSTIC_TEST: Multi-disciplinary assessment — Multi-disciplinary assessment including blood tests, CSF test, electrocardiograms, ultrasound, imaging, etc
Eligibility Ages 18 Years – 80 Years
HOPE From the Cerebellum: TMS-Induced Cognitive Recovery After Stroke
Zi-Xiao Li
n=70
Beijing Tiantan hospital
Beijing
Intervention DEVICE: iTBS group — iTBS on the contralesional cerebellum, twice a day for seven days
Eligibility Ages 18 Years
Effects of Cerebellar tACS-iTBS in Ataxia
I.R.C.C.S. Fondazione Santa Lucia
n=30
IRCCS Santa Lucia Foundation
Rome, Lazio
Intervention DEVICE: Real (real iTBS/tACS + exergaming) — Stimulation will be applied to the cerebellum. The tACS session duration will be 190 seconds with a frequency of 5 Hz co...
Eligibility Ages 8 Years – 80 Years
Gait Analysis Parameter and Upper Limb Evaluation in Adult Patients With Neurological or Metabolic Pathology
Centre Hospitalier Universitaire de Liege
n=300
Centre de référence des maladies neuromusculaire, Centre Hospitalier Régional de la Citadelle
Liège
Intervention DEVICE: Syde — Syde is an innovative device intended to be used in a home-based environment. It is composed of two watch-like sensors, ...
Eligibility Ages 18 Years
Sporadic Degenerative Ataxia With Adult Onset: Natural History Study
Ataxia Study Group
n=300
Department of Neurology, Medical University, Innsbruck
Innsbruck
Eligibility Ages 40 Years
Effects of Intermittent Theta Burst Stimulation (iTBS) on Motor Recovery of Lower Extremity in Chronic Stroke Patients
Danderyd Hospital
n=56
Department of Rehabilitation Medicine, Danderyd Hospital, Danderyd, Stockholm 18288
Stockholm
Intervention DEVICE: Intermittent Theta Burst Stimulation — iTBS protocol: 600 pulses at 80% of AMT for 190 sec on the contralesional cerebellum, targeted with the support of a neu...
Eligibility Ages 18 Years
A Multiple Ascending Dose Study of DT-216P2 in Patients With Friedreich's Ataxia
Design Therapeutics, Inc.
n=20
Scientia Clinical Research Ltd
Sydney, New South Wales
Intervention DRUG: DT-216P2 — Active
Eligibility Ages 18 Years – 65 Years
Efficacy of Omaveloxolone Treatment for Dysphagia in French Patients With Friedreich's Ataxia
Centre Hospitalier Universitaire de Nice
n=40
CHU NICE
Nice, Alpes Maritimes
Intervention DRUG: SKYCLARYS (omaveloxolone) — Skyclarys is indicated for the treatment of Friedreich's ataxia in adults and adolescents aged 16 and over. Opaque capsu...
Eligibility Ages 16 Years
Shunt-dependency After aSAH - Role of Early Hyperglycaemia in CSF and Blood
Isabel Hostettler
n=160
Cantonal Hospital Aarau
Aarau
Intervention DIAGNOSTIC_TEST: Cerebrospinal Fluid (CSF) Sample — Samples for glucose in CSF will be taken upon EVD/LD placement until EVD/LD removal (within the first 14 days).
Eligibility Ages 18 Years
Characterization of the Cardiac Phenotype of Friedreich's Ataxia (FRDA)
Weill Medical College of Cornell University
n=100
Weill Cornell Medicine
New York, New York
Intervention PROCEDURE: Cardiac magnetic resonance imaging (CMR) — CMR is a non-invasive way to take a high-resolution image of the heart and vessels. CMR uses powerful magnets and radio ...
Eligibility Ages 12 Years – 50 Years
Imaging Speech in Neurotypical Adults and Individuals With Cerebellar Stroke
University of Pittsburgh
n=100
University of Pittsburgh
Pittsburgh, Pennsylvania
Intervention BEHAVIORAL: Neural responses to speech functional localizer — Measuring speech-related brain activity using fMRI during a speech listening task.
Eligibility Ages 18 Years
Prophylactic Antibiotics Useful With Antibiotic Impregnated External Ventricular Drains (EVDs)?
Montefiore Medical Center
n=84
Montefiore Medical Center
The Bronx, New York
Intervention DRUG: Long term (continuous) prophylactic antibiotics — VRIs in patients who also receive a pre-procedural dose of antibiotics with continued dosing of antibiotics for the dura...
Eligibility Ages 18 Years
Cerebellar TMS and Satiety in Prader-Willi Syndrome
Brigham and Women's Hospital
n=20
McLean Hospital
Belmont, Massachusetts
Intervention DEVICE: Repetitive Transcranial Magnetic Stimulation (rTMS) — rTMS is a technique of TMS that allows for selective external manipulation of neural activity in a non-invasive manner. ...
Eligibility Ages 18 Years – 64 Years
Flow Detection in Open and Closed Shunt Valve Periods
Rhaeos, Inc.
n=55
OSF Healthcare
Peoria, Illinois
Intervention DEVICE: Rhaeos Shunt Monitoring System — characters, and fully aligned with your protocol: The intervention consists of use of a noninvasive, wireless thermal fl...
Cerebellar Deep Brain Stimulation or VNS for Chronic Post-stroke Motor Rehabilitation
Qilu Hospital of Shandong University
n=100
Chao Zhang
Jinan, Shandong
Intervention DEVICE: Bilateral Cerebellar deep brain stimulation — Participants underwent stereotactic implantation of a single DBS lead in the area of the cerebellar DN contralateral to ...
Eligibility Ages 30 Years – 75 Years
Interposed Nucleus aDBS for Ataxia
University of Florida
n=5
Norman Fixel Institute for Neurological Diseases
Gainesville, Florida
Intervention DEVICE: Deep Brain Stimulation — This device will be surgically implanted into the interposed nucleus of the cerebellum.
Eligibility Ages 21 Years – 89 Years
NIRS Monitoring in Premature Infants
Boston Children's Hospital
n=70
Boston Children's Hospital
Boston, Massachusetts
Intervention PROCEDURE: ETV/CPC — endoscopic third ventriculostomy (ETV) combined with choroid plexus cauterization (CPC) is a surgical procedure to treat...
Eligibility Ages 0 Months – 12 Months