Top Recruiting Trials
20 actively recruiting studies
Changing Tactics? Optimizing ECT in Difficult-to-treat Depression
Universitaire Ziekenhuizen KU Leuven
n=196
UPC Kortenberg
Kortenberg
Intervention DEVICE: switch to BT electrode position — use of different electrode positions of ECT device
Eligibility Ages 18 Years
Study of Ribociclib and Everolimus in HGG and DIPG or Ribociclib and Temozolomide in DHG, H3G34-mutant
Nationwide Children's Hospital
n=120
Children's Hospital Colorado
Aurora, Colorado
Intervention DRUG: Ribociclib — Ribociclib PO qd on days 1-21
Eligibility Ages 12 Months – 39 Years
GD2-CAR T Cells for Pediatric Brain Tumours
Bambino Gesù Hospital and Research Institute
n=54
Ospedale Pediatrico Bambino Gesù
Roma, Italy
Intervention BIOLOGICAL: GD2-CART01 (iC9-GD2-CAR T-cells) — Following a lymphodepleting treatment with conventional chemotherapy, patients will be treated with 1.0 to 6.0 x 10⁶/kg ...
Eligibility Ages 6 Months – 30 Years
Neuroimmunology Registry and Biobank
Charite University, Berlin, Germany
n=300
Charité - Universitätsmedizin Berlin
Berlin, State of Berlin
Multidimensional Evaluation of Patients' Affected by Obstructive Apnea Syndrome (OSAS) Before and After Ventilotherapy
Istituto Auxologico Italiano
n=65
IRCCS Istituto Auxologico Italiano
Piancavallo, VCO
Intervention DEVICE: Continuous Positive Airway Pressure Ventilotherapy — Breathing support device during sleeping
Eligibility Ages 20 Years – 60 Years
Parental Distress and Treatment Adherence in Pediatric Recurrent Medulloblastoma
West China Hospital
n=450
West China Hospital of Sichuan University
Chengdu, Sichuan
Intervention OTHER: Not applicable- observational study — Not applicable- observational study
Eligibility Ages 0 Years – 18 Years
UPenn Observational Research Repository on Neurodegenerative Disease
University of Pennsylvania
n=1000
University of Pennsylvania
Philadelphia, Pennsylvania
Intervention OTHER: No intervention — No intervention
Eligibility Ages 18 Years
Molecular and Clinical Risk-Directed Therapy for Infants and Young Children With Newly Diagnosed Medulloblastoma
St. Jude Children's Research Hospital
n=130
Lucille Packard Children's Hospital Stanford
Palo Alto, California
Intervention PROCEDURE: Surgical resection — All participants enrolled will undergo surgical resection prior to treatment. The maximal resection that can be achieved...
Eligibility Ages 59 Months
Structural Heat Adaptation and Education in Rural Setting
Aga Khan University
n=7128
Aga Khan University Hospital
Matiari
Intervention BEHAVIORAL: Community education and awareness — This component of the ReHAB will be achieved through community mobilization, which will encompass awareness and motivati...
Time Restricted Eating for WeIght LoSs MainTenance-2
NYU Langone Health
n=110
NYU Langone Health
New York, New York
Intervention BEHAVIORAL: TRE — Participants randomized to the TRE arm will be instructed to consume all food and beverages in a self-selected 10-hr eat...
Eligibility Ages 25 Years – 65 Years
Mississippi Delta Community Care Home Visits Program
Jackson State University
n=500
Mississippi State Department of Health
Jackson, Mississippi
Intervention BEHAVIORAL: The PEN-3 Intervention Model — The PEN-3 Model is a sociocultural model for planning and assessing participant behavior within the context a cultural p...
Eligibility Ages 18 Years – 45 Years, FEMALE only
Accelerated iTBS for Major Depression
Istanbul University - Cerrahpasa
n=35
Istanbul University - Cerrahpasa
Istanbul
Intervention DEVICE: Accelerated Intermittent Theta Burst Stimulation (iTBS) — Accelerated intermittent theta burst stimulation (iTBS) is administered bilaterally to the dorsomedial prefrontal cortex...
Eligibility Ages 18 Years – 65 Years
A Phase 0/1 Study of cDNA for TP53, Checkpoint Inhibition and Radiation in Children With Recurrent, Progressive or Refractory CNS Malignancies.
Children's National Research Institute
n=18
Children's National Hospital
Washington D.C., District of Columbia
Intervention DRUG: SGT-53 — SGT-53 is a novel cationic liposome encapsulating a normal human wild type TP53 cDNA sequence in a plasmid backbone. The...
Eligibility Ages 3 Years – 21 Years
Improving Mobility After Revascularization in Peripheral Artery Disease
Northwestern University
n=386
University of Arizona
Tucson, Arizona
Intervention BEHAVIORAL: Home Based Exercise — This is a six month intervention where participants will walk at home for exercise with guidance from a study coach. The...
Eligibility Ages 18 Years
Using Neuroimaging and Behavioral Assessments to Understand Late Talking
University of Toronto
n=45
Grandview Kids
Oshawa, Ontario
Intervention BEHAVIORAL: Intervention to address late talking — this intervention is designed to support both speech and language development in children who are toddlers. Given the ag...
Eligibility Ages 18 Months – 30 Months
The Impact of Wearing the Hijab on Whole-body Heat Loss During Exercise-heat Stress
University of Ottawa
n=12
University of Ottawa
Ottawa, Ontario
Intervention OTHER: Exercise-heat stress with no hijab — Participants perform exercise in the heat with no hijab
Eligibility Ages 18 Years – 35 Years, FEMALE only
Clinical and Neurobehavioral Changes With Weight Loss Drug Discontinuation and Reinitiation
The University of Texas at Dallas
n=40
Center for BrainHealth
Dallas, Texas
Intervention OTHER: Discontinuation and Reinitiation of Tirzepatide — Participants will temporarily pause their tirzepatide medication for 3-4 weeks and then restart it for 6-8 weeks under t...
Eligibility Ages 18 Years – 70 Years
tDCS as Treatment for Motor Function
Baycrest
n=20
Baycrest Academy of Health Sciences and Geriatric Research
Toronto, Ontario
Intervention DEVICE: Transcranial direct current stimulation (TDCS) — The Crossover design will enable us to use each participant as their own control.
HOPE From the Cerebellum: TMS-Induced Cognitive Recovery After Stroke
Zi-Xiao Li
n=70
Beijing Tiantan hospital
Beijing
Intervention DEVICE: iTBS group — iTBS on the contralesional cerebellum, twice a day for seven days
Eligibility Ages 18 Years
Effects of Cerebellar tACS-iTBS in Ataxia
I.R.C.C.S. Fondazione Santa Lucia
n=30
IRCCS Santa Lucia Foundation
Rome, Lazio
Intervention DEVICE: Real (real iTBS/tACS + exergaming) — Stimulation will be applied to the cerebellum. The tACS session duration will be 190 seconds with a frequency of 5 Hz co...
Eligibility Ages 8 Years – 80 Years