Top Recruiting Trials
20 actively recruiting studies
A Novel Extracorporeal Liver Support Therapy In ALCF and to Evaluate the Efficacy of DIALIVE 2.0, a Liver Dialysis Device.
Yaqrit Ltd
n=72
Royal Free Hospital
London, Greater London
Intervention OTHER: Standard of Care (Investigator Choice) — Standard of care as per Investigator discretion
Eligibility Ages 18 Years – 70 Years
Liver Cirrhosis Network Rosuvastatin Efficacy and Safety for Cirrhosis in the United States
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
n=260
University of California San Diego NAFLD Research Center
La Jolla, California
Intervention DRUG: Rosuvastatin — Patients meeting all eligibility criteria will be assigned to a randomization arm prior to initiation of a 4-week lead-i...
Eligibility Ages 18 Years – 75 Years
Prospective Cohort for Early Detection of Liver Cancer
University of Oxford
n=3000
Hepatology Clinical Trial Unit, John Radcliffe Hospital
Oxford, Oxfordshire
Intervention OTHER: Blood and Urine samples — The samples will be used to identify a range of tests (including genetic, protein and other biomarkers), which along wit...
Eligibility Ages 18 Years – 100 Years
Assessing Signatures for Fibrosis Detection in Chronic Liver Disease: A Step Beyond Conventional Biomarkers
Universitair Ziekenhuis Brussel
n=110
UZ Brussel
Brussels
Intervention OTHER: Blood draw for biomarkers — EDTA tube Blood draw for biomarkers
Eligibility Ages 18 Years
A Study of Zunveyl on Safety, Tolerability, Neuropsychiatric Symptoms, and Caregiver Distress in Alzheimer's Disease (RESOLVE)
Alpha Cognition, Inc
n=150
Progeny Psychiatric Clinic - Irvine
Irvine, California
Intervention DRUG: Zunveyl® — Zunveyl® delayed release oral tablets.
Eligibility Ages 50 Years
The Effect of Laparoscopic Splenectomy on Liver Reserve Function for Cirrhosis Patients
Northern Jiangsu People's Hospital
n=20
Clinical Medical College of Yangzhou University
Yangzhou, Jiangsu
Intervention PROCEDURE: Laparoscopic splenectomy — The laparoscopic splenectomy was performed by the same surgical team.
Eligibility Ages 18 Years
Single and Multiple Dose Escalation of PHIN-214 in Child-Pugh A and B Liver Cirrhotics
PharmaIN
n=74
Arizona Liver Health
Chandler, Arizona
Intervention DRUG: PHIN-214 Subcutaneous injection — subcutaneous injection(s) with PHIN-214 terlipressin derivative
Eligibility Ages 18 Years – 75 Years
Evaluation of Cirrhotic Cardiomyopathy by Cardiac MRI in Patients Waiting for Liver Transplant.
Centre Hospitalier Universitaire de Besancon
n=60
CHU Besancon - Hopital Minjoz
Besançon
Intervention DIAGNOSTIC_TEST: MRI — The examination lasts between 45 minutes and one hour. The patient lies down in the MRI tube. He is fitted with headphon...
Eligibility Ages 18 Years – 70 Years
Hospital @ Home Model of Care for Cirrhosis
Indiana University
n=30
IU School of Medicine
Indianapolis, Indiana
Intervention OTHER: Indiana University Health Hospital at Home Program — Structure of Care in IUH H@H Program: The IUH H@H program allows patients to be cared for at home using home remote moni...
Eligibility Ages 18 Years
The Influence of Nutritional Factors on the Prognosis of Liver Cirrhosis Patients and the Exploration of Predictive Models
Juan Kang
n=300
The Second Affiliated Hospital of Chongqing Medical University
Chongqing, Chongqing Municipality
Eligibility Ages 18 Years – 75 Years
Study of the Test-retest Reliability of the Neuropsychiatric Fluctuations Scale in Parkinson's Disease
University Hospital, Grenoble
n=100
CHUGA
Grenoble
Intervention OTHER: Questionnaire and Physical Exam — self administered questionnaires
Eligibility Ages 30 Years – 75 Years
Feasibility of Wearables in Dementia Care in Rural Taiwan
China Medical University Hospital
n=20
China Medical University Beigang Hospital
Beigang, Yunlin
Intervention DEVICE: Re-Timer (light therapy glasses) — an eyewear emitting specific wavelength of green light.
Role of Allopurinol in Prevention of Complications Related to Decompensated Cirrhosis of Liver
Bangladesh Medical University
n=54
Department of Hepatology at Bangladesh Medical University.
Dhaka, Shahbagh
Intervention DRUG: Allopurinol Tablet — Patients will recieve 300 mg of Allopurinol daily along with standard medical therapy
Eligibility Ages 18 Years – 70 Years
Study of the Link Between MASH ( Metabolic Dysfunction-Associated Steatohepatitis) and MAMs (Mitochondria-Associated Membranes ) Alteration in Patients Undergoing Bariatric Surgery - MAMBA
Hospices Civils de Lyon
n=20
Hospices Civils de Lyon - Hôpital Edouard Herriot
Lyon, France
Intervention PROCEDURE: Bariatric surgery (Sleeve Gastrectomy or Gastric Bypass) — Patients undergoin bariatric surgery with simultaneous liver biopsy to analyze MAMs alterations in liver and PBMCs. Foll...
Eligibility Ages 18 Years – 99 Years
CirrhosisRx CDS System
University of California, San Francisco
n=2106
University of California San Francisco Medical Center
San Francisco, California
Intervention OTHER: CirrhosisRx CDS — CirrhosisRx is a cirrhosis-specific CDS that organizes clinical data into clinically relevant groupings and links them t...
Eligibility Ages 18 Years
Analysis of Methylomic Features and Prognostic Risk Prediction in Patients With Hepatitis B-related Acute-on-chronic Liver Failure
Qilu Hospital of Shandong University
n=100
Qilu Hospital of Shandong University
Jinan, Shandong
Eligibility Ages 18 Years
LEOPARD Prospective Validation Cohort 1
Assistance Publique - Hôpitaux de Paris
n=630
Department of Gastroenterology and Hepatology Universitair Ziekenhuis Gent
Ghent, Belgium
Intervention OTHER: Standardized assessments, guided tumor biopsy and biobanking — Standardized assessment of Scores
* Guided tumor biopsy in patients listed for hepatocellular carcinoma with active tum...
Eligibility Ages 18 Years – 70 Years
Liver-gut Axis Study Through Identification of Liver Disease-specific Microbiome
Chungnam National University Hospital
n=3000
Chungnam National University Hospita
Daejeon, Jung-gu
Eligibility Ages 19 Years
Role for Biochemical Assays and Kayser-Fleischer Rings in Diagnosis of Wilson Disease
Second Affiliated Hospital, Zhejiang University, School of Medicine
n=1000
Second Affiliated Hospital, Zhejiang University School of Medicine
Hangzhou, Zhejiang
Intervention DIETARY_SUPPLEMENT: low copper diet — All patients with wilson disease should receive low copper diet
Eligibility Ages 6 Years – 65 Years
Cardiac Involvement in Wilson's Disease
Fondation Ophtalmologique Adolphe de Rothschild
n=150
Fondation Adolphe de Rothschild
Paris
Intervention PROCEDURE: Delivery of a long-term Holter 21 days Or placement of an implantable holter from the outset so syncope — The intervention consists of setting up a morphological and rhythmological cardiological follow-up of patients with conf...
Eligibility Ages 18 Years